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(一) 書籍類 1. Wynn HT Pan, P Kumari, and CC Lin (1992) Determination of a new oral cephalosporin in biological fluids, in Chromatography of Pharmaceuticals:Natural, Synthetic, and Recombinant Products (Satinder Ahuja, eds.), pp. 144-157, American Chemical Society, Washington, D.C. 2. L Alexander, V Maggio, J Gill, W Turner, D Patterson, A Seed, S Gethis, V Green, J Brock, and Wynn HT Pan (1990) “Comparison of 2,3,7,8-dibenzo-p-dioxin chlorine isotope ratio measurements using electron multiplier and photomultiplier detectors”, in Organohalogen Compounds, Vol. 2, EPRI PCB, Analysis, QA/QC, Brominated Compounds, Short Chain Aliphatics (O. Hutzinger and H. Fielder, eds.), pp. 77-79, Ecoinforma Press, Bayreuth, Germany. (二) 科學論文類 1. JM Cheng, JQ Liu, JH Liu, Wynn HT Pan, XM Zhang, L Hu, HM Chao (2016) Chi-Ju-Di-Huang-Wan protects against retinal ischemia by downregulating matrix metalloproteinase-9 via p38 mitogen-activated protein kinase inhibition in the rat. Chin Med (accepted). 2. HJ Shih, JC Yen, AW Chiu, YC Chow, Wynn HT Pan, TY Wang, CJ Huang (2016) FTY720 mitigates germ cell apoptosis in testicular torsion/Detorsion. J Surg Res 202: 155-164. 3. HJ Shih, JC Yen, AW Chiu, YC Chow, Wynn HT Pan, TY Wang, CJ Huang (2015) FTY720 mitigates torsion/detorsion-induced testicular injury in rats. J Surg Res 196(2): 325-331. 4. G Weng, S Han, R Pu, Wynn HT Pan, LW Shi (2014) Exploration of approaches to adjusting brand-name drug prices in Mainland of China: based on comparison and analysis of some brand-name drug prices of Mainland and Taiwan, China. Chin Med J 127(12): 2222-2228. 5. XQ Liu, BJ Wu, Wynn HT Pan, XM Zhang, JH Liu , MM Chen, FP Chao, HM Chao (2013) Resveratrol mitigates rat retinal ischemic injury: the roles of matrix metalloproteinase-9, inducible nitric oxide, and heme oxygenase-1. J Ocul Pharmacol Ther 29(1):33-40. 6. JH Liu, MJ Chuang, XQ Liu, LK Ho, Wynn HT Pan, XM Zhang, CM Liu, MY Yeh, SK Tsai, CW Kon, SD Lee, MM Chen, FP Chao, HM Chao (2013) Baicalein protects against retinal ischemia by antioxidation, antiapoptosis, downregulation of HIF-1a, VEGF, and MMP-9 and upregulation of HO-1. J Ocul Pharmacol Ther 29(6):539-549. 7. YQ Chen, Wynn HT Pan, JH Liu, MM Chen, CM Liu, MY Yeh, SK Tsai, MS Young, XM Zhang, HM Chao (2012) The Effects and underlying mechanisms of S-allyl L-cysteine treatment of the retina after ischemia/reperfusion. J Ocul Pharmacol Ther 28(2):110-117. 8. JH Liu, H Wann, MM Chen, Wynn HT Pan, YC Chen, CM Liu, MY Yeh, SK Tsai, MS Young, HY Chuang, FP Chao, HM Chao (2010) Baicalein significantly protects human retinal pigment epithelium cells against H2O2-induced oxidative stress by scavenging reactive oxygen species and downregulating the expression of matrix metalloproteinase-9 and vascular endothelial growth factor. J Ocul Pharmacol Ther 26(5):1-9. 9. JH Liu, MM Chen, JW Huang, H Wann, LK Ho, Wynn HT Pan,YC Chen, CM Liu, MY Yeh, SK Tsai, MS Young, LT Ho , CD Kuo, HY Chuang, FP Chao, HM Chao (2010) Therapeutic effects and mechanisms of action of mannitol during H2O2-induced oxidative stress in human retinal pigment epithelium cells. J Ocul Pharmacol Ther 26(3):249-257. 10. PL Yu, CI Wu, TS Lee, Wynn HT Pan, P Wang, SW Wang (2009) Estradiol attenuated the reduction of striatal dopamine by amphetamine in ovariectomized rats. J Cell Biochem 108(6):1318-1324. 11. HM Chao, YH Chen, JH Liu, SM Lee, FL Lee, Y Chang, PH Yeh, Wynn HT Pan, CW Chi, TY Liu, WY Lui, LT Ho, CD Kuo, DE Lin, CC Chan, DM Yang, AMY Lin, FP Chao (2008) Iron-generated hydroxyl radicals kill retinal cells in vivo: effect of ferulic acid. Hum Exp Toxicol 27(4):327–339. 12. HM Chao, DE Lin, Y Chang, WM Hsu, SM Lee, FL Lee, CW Chi, Wynn HT Pan, TY Liu, WY Lui, LT Ho, CD Kuo, CC Chan, FP Chao (2008) Ferulic acid, but not tetramethylpyrazine, Significantly attenuates retinal ischemia/reperfusion-induced alterations by acting as a hydroxyl radical scavenger. J Ocul Pharmacol Ther 24(5):461-472. 13. SK Lin, Wynn HT Pan, PH Yeh (2007) Prefrontal dopamine efflux during exposure to drug-associated contextual cues in rats with prior repeated methamphetamine. Brain Res Bull 71: 365-371. 14. Wynn HT Pan, MC Hsieh, HH Wu, SK Lin (2006) Difference in magnitude of psychostimulant-induced extracellular norepinephrine in the ventral tegmental area contributes to discrepant prefrontal dopamine outflow. Addict Biol 12: 51-58. 15. YY Liu, PH Yeh, GJ Wang, SW Huang, CW Chi, LK Ho, Wynn HT Pan (2006) Baicalein reverses the methamphetamine induced striatal dopaminergic neurotoxicity in mice. J Food Drug Anal 14(4): 317-322. 16. HH Wu, CR Lee, SK Lin, PH Yeh, Wynn HT Pan (2006) A Single intrategmental amphetamine exposure induces transient behavioral sensitization in the rats. Chinese J Physiol 49(1): 14-21. 17. CJ Huang, PS Tsai, Wynn HT Pan, JW Skimming (2005) Microdialysis for measurement of hepatic and systemic nitric oxide biosynthesis in septic rats. Acta Anaesthesiol Scand 49, 28-34 18. MR Fuh, CH Haung, TY Wu, SL Lin, Wynn HT Pan (2004) Determination of amphetamine in rat brain by in vivo microdialysis and ion-pairing liquid chromatography with electrospray tandem mass spectrometry. Rapid Commun Mass Sp 18, 1711-1714. 19. CJ Huang, PS Tsai, CH Yang, TH Su, BR Stevens, JW Skimming, Wynn HT Pan (2004) Pulmonary transcription of CAT-2 and CAT-2B but not CAT-1 and CAT 20. CJ Huang, PS Tsai, YT Lu, CR Cheng, BR Stevens, JW Skimming, Wynn HT Pan (2004) NF-κB involvement in the induction of high affinity CAT 21. Wynn HT Pan, SY Yang, SK Lin (2004) Neurochemical interaction between dopaminergic and noradrenergic neurons in the medial prefrontal cortex. Synapse 53, 44-52. 22. MR Fuh, CH Haung, SL Lin, Wynn HT Pan (2004) Determination of free-form amphetamine in rat brain by ion-pair liquid chromatography-electrospray mass spectrometry with in vivo microdialysis. J Chromatography A 1031, 197-201. 23. SK Lin, SH Wu, YS Yang, Wynn HT Pan (2003) Drug addiction --- the neurochemical perspective of brain in drug-seeking behavior. J Food Drug Anal 11(4), 344-352. 24. MR Fuh, HT Lin, Wynn HT Pan, FR Lin (2002) Simultaneous determination of free-form amphetamine in rat’s blood and brain by in-vivo microdialysis and liquid chromatography with fluorescence detection. Talanta 58, 1357-1363. 25. JJ Hwang, M. Liao, TC Yen, SP Wey, KJ Lin, Wynn HT Pan, JC Chen, G Ting（2002）Biodistribution study of [ 26. MS Fuh, YL Tai, Wynn HT Pan （2001）Determination of free-form of cocaine in rat’s brain by liquid chromatography-electrospray mass spectrometry with in vivo microdialysis. J Chromatogr B 752, 107-114. 27. NNH Chen, Wynn HT Pan (2000) Regulatory effects of D2 receptors in the ventral tegmental area on the mesocorticolimbic dopaminergic pathway. J Neurochem 74(6): 2576-2582. 28. YJ Lai, EY Shen, Wynn HT Pan (2000) Effects of ascorbate in the microdialysis perfusion medium on the extracellular basal concentration of glutamate in rat’s striatum. Neurosci Lett 279: 145-148. 29. MS Fuh, YF Chen, Wynn HT Pan, IP Huang (1999) Analysis of flunarizine in rat’s brain by liquid chromatography with UV/visible detection. J Liq Chrom & Rel Technol 22(16): 2525-2533. 30. YL Yang, Wynn HT Pan, TH Chiu, MT Lin (1998) Striatal glutamate release is important for development of ischemic damage to striatal neurons during rat heatstroke. Brain Res 795: 121-127. 31. NNH Chen, YJ Lai, Wynn HT Pan (1997) Effects of different perfusion medium on the extracellular basal concentration of dopamine in striatum and medial prefrontal cortex: a zero-net flux microdialysis study. Neurosci Lett 225: 197-200. 32. Wynn HT Pan, SJ Lin, KH Chang, MH Lee (1997) Supercritical carbon dioxide extraction of eighteen natural products. Chemistry 55(4): 87-90. 33. MS Fuh, TK Wang, Wynn HT Pan (1997) Determination of free-form amphetamine concentration in rat’s brain by in vivo microdialysis and liquid chromatography with fluorescence detection. J Liq Chrom & Rel Technol 20(10): 1605-1615 34. Wynn HT Pan, NNH Chen, FY Tsai, HY Liao (1996) Intrategmental infusion of cocaine decreases dopamine and enhances norepinephrine release in the medial preforntal cortex. Eur J Pharmacol 317: 205-213. 35. Wynn HT Pan, CR Lee, LH Lim (1996) A new video path analyzer to monitor travel distance, rearing, and stereotypic movement of rats. J Neurosci Methods 70: 39-43. 36. Wynn HT Pan, JC Sung, MS Fuh (1996) Locally application of amphetamine into the ventral tegmental area enhances dopamine release in the nucleus accumbens and the medial prefrontal cortex through noradrenergic neurotransmission. J Pharmacol Exp Ther 278(2): 725-731 37. MS Fuh, GT Lue, SH Ke, Wynn HT Pan (1996) Supercritical carbon dioxide extraction or red cypress sawdust: a comparison of solvent extraction and steam distillation methods. Yaowu Shipin Fenxi 4(3): 203-2214. 38. MR Fuh, Wynn HT Pan, IJ Hsieh, CM Chuo (1995) Preparative supercritical fluid extraction of essential oils from Syzygium Aromaticum (glove bud). American Lab 12: 36-41. 39. Wynn HT Pan, CC Chang, TT Su, F Lee, MR Fuh (1995) Preparative supercitical fluid extraction of pyrethrin l and ll from pyrethrum flower. Talanta 42: 1745-1749. 40. Wynn HT Pan, BF Hsieh, KH Chang, G. Duh (1995) Supercritical carbon dioxide extraction of Saussureae Radix and analyzing its composition. Chemistry 53: 155-162. 41. Wynn HT Pan, JC Lee (1995) Determination of microdialysis extraction fraction of cocaine by the no net flux method under high, low, and zero steady-state cocaine concentrations in rats. Brain Res 686: 249-253. 42. Wynn HT Pan, YJ Lai (1995) Anesthetics decreased the microdialysis extraction fraction of norepinephrine but not dopamine in the medial prefrontal cortex. Synapse 21: 85-92. 43. Wynn HT Pan, YJ Lai , NNH Chen (1995) Differential effects of chloral hydrate and pentobarbital sodium on a cocaine level and its catecholamine response in the medial prefrontal cortex: a comparison with conscious rats. J Neurochem 64: 2653-2659. 44. Wynn HT Pan, CK Liu, LY Chou, BF Hsieh, MH Lee (1994) Supercritical carbon dioxide extraction of Cinnamomi Cortex: in comparison with a steam distillation method. J Chinese Medicine 5: 199-207. 45. NNH Chen, YJ Lai, CF Chen, Wynn HT Pan (1994) In vivo microdialysis: a novel sampling technique for drug analysis in live subjects. Yaowu Shipin Fenxi 2: 149-154 46. MY Tsou, WB Len, TY Lee, SHH Chan, Wynn HT Pan, JYH Chan (1994) Participation of noradrenergic neurotransmission in the suppression by substance P of alpha2-adrenoceptors at the nucleus reticularis gigantocellularis involved in central cardiovascular regulation in the rat. Brain Res 653: 183-190. 47. Wynn HT Pan, LH Lim, MR Shiau (1994) Difference in extracellular cocaine concentration between the ventral tegmental area and the medial prefrontal cortex following intravenous administration as revealed by quantitative microdialysis coupled with in vivo calibration. J Neurosci Methods 53: 65-71. 48. Wynn HT Pan, CK Liu, LY Chou, MH Lee (1994) Supercritical carbon dioxide extraction of Angelicate Radix, Amoni Semen, and Caryophylli Flos. J Chinese Medicine 5: 71-78. 49. Wynn HT Pan, NNH Chen, YJ Lai , HF Luoh (1994) Differential effects of chloral hydrate and pentobarbital sodium on cocaine-induced electroencephalographic desynchronization at the medial prefrontal cortex in rats. Life Sci 54: PL 419-424. 50. HF Luoh, TBJ Kuo, SHH Chan, Wynn HT Pan (1994) Power spectral analysis of electroencephalographic desynchronization induced by cocaine in rats: correlation with microdialysis evaluation of dopaminergic neurotransmission at the medial prefrontal cortex. Synapse 16: 29-35. 51. PPC Tan, MH Shyr, CH Yang, TBJ Kuo, Wynn HT Pan, SHH Chan(1993) Power spectral analysis of the electroencephalographic and hemodynamic correlates of propofol anesthesia in the rat: intravenous infusion. Neurosci Lett 160: 205-208. 52. MH Shyr, CH Yang, TBJ Kuo, Wynn HT Pan, PPC Tan, SHH Chan (1993) Power spectral analysis of the electroencephalographic and hemodynamic correlates of propofol anesthesia in the rat: intravenous bolus administration. Neurosci Lett 153: 161-164. 53. Wynn HT Pan, P Kumari, JAF DeSilva, CC Lin (1993) Determination of ceftibuten in sputum by column switching high-performance liquid chromatography on-line with thermospray mass spectrometry. J Pharm Sci 82(1): 52-55. 54. Wynn HT Pan, P Kumari, J Lim, CC Lin (1992) Determination of a cephalosporin antibiotic, ceftibuten, in human plasma by column-switching high-performance liquid chromatography using ultraviolet detection. J Pharm Sci 81(3): 663-666. 55. Wynn HT Pan, S Menecherry, JB Justice, Jr. (1991) Differences in the pharmacokinetics of cocaine in naive and cocaine experienced rats. J Neurochem 56: 1299-1306. 56. SHH Chan, Wynn HT Pan (1992) Future development of research techniques in neurosciences. Bioindustry 3(12): 23-25. 57. Wynn HT Pan, P Mojavorian (1991) Steady state cocaine concentrations in the nucleus accumbens following two dosing regimen in rats. Res Commu Sub Abu 12(4): 185-196. 58. Wynn HT Pan, S Menecherry, JB Justice, Jr. (1991) Differences in the pharmacokinetics of cocaine in naive and cocaine experienced rats. J Neurochem 56: 1299-1306. 59. HO Pettit, Wynn HT Pan, LH Parsons, JB Justice, Jr. (1990) Extracellular concentrations of cocaine and dopamine are enhanced during chronic cocaine administration. J Neurochem 55: 798-804. 60. LC Nicolaysen, Wynn HT Pan, JB Justice, Jr. (1988) Extracellular cocaine and dopamine concentrations are linearly related in rat striatum. Brain Res 456: 317-323.
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