Side effect of alpha lipoic acid（ALA）

血糖可能會降得太低，需要經常監控血糖濃度。

硫辛酸也可能會降低體內礦物質，例如鐵。

硫辛酸與制酸劑胃藥有交互作用

可能會降低某些抗癌藥物的效果。

其他少見的可能副作用還包括了頭痛、皮膚癢和腸胃不適。 

糖尿病患者在服用此補充劑時應仔細監測自己的血糖水平，以避免發生低血糖。

＊ 一般來說，補充ALA幾乎沒有嚴重的副作用。外消旋ALA的劑量為600毫克/天，持續3週，靜脈注射，口服外消旋ALA的劑量高達1800毫克/天，持續6個月和1200毫克當用於治療糖尿病週邊神經病變時，每天一次，持續2 年，沒有導致嚴重的不良反應。靜脈注射ALA 後，報告了兩種輕微的過敏樣反應和一種嚴重的過敏反應，包括喉痙攣。口服ALA 補充劑最常報告的副作用是影響皮膚的過敏反應，包括皮疹、蕁麻疹和瘙癢。也報告了胃腸道症狀，包括腹痛、噁心、嘔吐和腹瀉。口服1200 毫克/天ALA 的人還發現尿液有惡臭。

＊people with diabetes should follow their blood sugar levels carefully when taking this supplement in order to avoid hypoglycemia (low blood sugar). 

＊    In general, ALA supplementation has been found to have few serious side effects. Intravenous administration of racemic ALA at doses of 600 mg/day for 3 weeks and oral racemic ALA at doses as high as 1800 mg/day for 6 months and 1200 mg/day for 2 years did not result in serious adverse effects when used to treat diabetic peripheral neuropathy. Two minor anaphylactoid reactions and one severe anaphylactic reaction, including laryngospasm, were reported after intravenous ALA administration. The most frequently reported side effects to oral ALA supplementation are allergic reactions affecting the skin, including rashes, hives and itching. Gastrointestinal symptoms, including abdominal pain, nausea, vomiting and diarrhea have also been reported. Malodorous urine has also been noted by people taking 1200 mg/day of ALA orally.