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》資料庫管理系統-分組報告-譯文part.4
2007/12/23 00:06:48瀏覽344|回應0|推薦1

Online Mendelian Inheritance in Man.


Online Mendelian Inheritance in Man (OMIN) is an electronic compendium of information on the genetic basis of human disease.

以人類疾病為分類基因基礎建構的電子資訊綱要。

Begun in hard copy form by Victor McCusick in 1966 with 1,500 entries, it was converted to a full text electronic form between 1987 and 1989 by the GDB.

1966年由Victor McCusick以硬碟拷貝1,500個單位,並在1987年與1989年之間由GDB轉為電子全文格式。

In 1991, its administration was transferred from Johns Hopkins University to the NCBI, and the entire database was converted to NCBI’s GenBank format.

1991年,由約翰霍普金斯大學遷到NCBI管理,並將整個資料庫轉為NCBIGenBank 形式。

Today it contains more than 16,000 entries.

今天它已包含超過16000個單位。


OMIN covers material on five disease areas based loosely on organs and systems.

OMIN主要以疾病在器官和系統上,粗略的分成5個區域。

Any morphological, biochemical, behavioral, or other propertied under study are referred to as phenotype of an individual (or a cell).

在研究形態學、生物化學、行為,或者其他生物和細胞有關的表現型。

Mendel realized that genes can exist in numerous different forms known as alleles.

孟德爾意識到基因能以不同型式的等位基因存在。

A genotype refers to the actual allelic composition of an individual.

基因型則指個體實際的等位基因型組成。


The structure of the phenotype and genotype entries contains textual data loosely structured as general descriptions, nomenclature, modes of inheritance, variations, gene structure, mapping, and numerous lesser categories.

表現型和基因型的個體架構含較一般的描述,而非精確組織的原文數據,像是繼承、變化、基因架構、繪圖和許多較小種類的命名法、模式等。

The full text entries were converted to an ASN.1 structured format when OMIN was transferred to the NCBI. This greatly improved the ability to link OMIN data to other databases and it also provided a rigorous structure for the data.

OMIN被轉移到NCBI時,便改以ASN.1語法架構。大大改進OMIN的資料和其他資料庫的連結能力,並為資料提供一個嚴謹的架構。

However, the basic form of the database remained difficult to modify.

然而資料庫的基本形式仍難以修改。



原文截自Fundamentals of DATABASE  SYSTEMS,FIFTH EDITION

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