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2007/12/22 23:34:34瀏覽297|回應0|推薦0 | |
The Human Genome Project and Existing Biological Database 人類基因工程與現有生物資料庫 The term genome is defined as the total genetic information that can be obtained about an entity. 基因組定義為構成單一個體所有遺傳物質的總和 The human genome, for example, generally refers to the complete set of genes required to create a human being ─ estimated to be more than 25,000 genes spread over 23 pairs of chromosomes, with an estimated 3 to 4 billion nucleotides. 例如,人類基因組即包含23對染色體,其中估計有超過25,000個基因,30或40億個核酸 The goal of the Human Genome Project (HGP) has been to obtain the complete sequence ─ the ordering of the bases ─ of those nucleotides. 人類基因工程(HGP)的目標即是針對基本的核酸進行完整的定序 A rough draft of entire human genome sequence was announced in June 2000 and published in 2001. 個人基因定序的草圖已於2000年6月發表並在2001年出版 The genome is complete with 99.9% accuracy. 當中99.9%的基因組已完成解讀。 In isolation, the human DNA sequence is not particularly useful.However, the sequence can be combined with other data and used as a powerful tool to help address questions in genetics, biochemistry, medicine, anthropology, and agriculture. 單獨來看,人類的DNA序列並非有特殊用途,但可與其他資料結合,作為遺傳學、生物化學、醫學、人類學和農業上基因定位的有力工具。 In the existing genome databases, the focus has been on curating ( or collecting with some initial scrutiny and quality check ) and classifying information about genome sequence data. 現有的基因資料庫多集中在curating上,(或最初檢視、質量檢查),並將基因順序的資料進行分類。 In addition to the human genome, numerous organisms such as E. coli, Drosophila, and C. elegans have been investigated. 除了人類基因,像是E. coli, Drosophila和C. elegans等的許多生物體已被調查。 We will briefly discuss some of the existing database systems and information systems that are supporting or have grown out of the Human Genome Project. 我們將簡要的探討支援人類基因工程的一些現有資料庫系統和資訊系統。 原文截自Fundamentals of DATABASE SYSTEMS,FIFTH EDITION 腦殘自翻,高手請指正錯誤地方(跪) |
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