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2007/12/22 23:59:29瀏覽612|回應0|推薦0 | |
The Genome Database (GDB). Created in 1989, the Genome Database (GDB) is a catalog of human gene mapping data, a process that associates a piece of information with a particular location on the human genome. 於1989年建立,以人類基因的圖表數據為目錄,將片斷訊息和相對的特別序列相互聯繫。 The degree of precision of this location on the map depends upon the source of the data, but it is usually not at the level of individual nucleotide bases. 定序位置的經度在圖上由資料的來源決定,但通常不在個體的基本核酸中。 GDB data includes data describing primarily map information (distance and confidence limits), and Polymerase Chain Reaction (PCR) probe data (experimental conditions, PCR primers, and reagents used). GDB資料包括主要描述圖表訊息的資料(距離和信任限制),以及Polymerase Chain Reaction (PCR) 探查數據(實驗工況,PCR 入門和使用試劑)。 More recently efforts have been made to add data on mutations linked to genetic loci, cell lines used in experiments, DNA probe libraries, and some limited polymorphism and population data. 近年來已成功透過實驗,增加與遺傳學基因定序相關的突變數據、DNA 探查圖書館和有限的polymorphism 與人口數據。 The GDB system is built around SYBASE, a commercial relation DBMS, and its data is modeled using standard Entity-Relationship techniques (see chapter 3 and 4). GDB系統由SYBASE 以ER-Model模式建置,屬於商業的關聯式資料庫管理系統。 The implementers of GDB have noted difficulties in using this mode to capture more than simple map and probe data. 實行上已發現透過簡單地圖和搜尋資料的模式有使用上的困難。 In order to improve data integrity and to simplify the programming for application writers, GDB distributes a Database Access Toolkit. 為了改善數據,並令使用者部分的程式得到簡化,GDB於工具箱中加入資料庫。 However, most users use a Web interface to search the ten interlinked data managers. 但,許多使用者透過同一Web 界面搜尋10筆相關的資料管理。 Each manager keeps track of the links (relationships) for one of the ten tables within the GDB system. 而每個資料管理和GDB系統的關係僅為10分1。 As with GenBank, users are given only a very high-level view of the data at the time of searching and thus cannot easily make use of any knowledge gleaned from the structure of the GDB tables. 像GenBank一樣,每次搜尋僅提供一個進階資料,因此無法簡單的從GDB的架構下搜尋所需的任何知識。 Search methods are most useful when users are simply looking for an index into map or probe data. 但當用戶僅僅尋找一個索引地圖或搜尋數據時,搜索法非常有用。 Exploratory ad hoc searching of the database is not encouraged by present interfaces. 目前的界面並不支援完整檢索與資料庫搜尋。 Integration of the database structures of GDB and OMIN (see below) was never fully established. 至於綜合GDB和OMIN(如下)的資料庫架構則從未完整建立。 原文截自Fundamentals of DATABASE SYSTEMS,FIFTH EDITION 腦殘自翻,高手請指正錯誤地方(跪) |
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