Every year routine check-up, always have a lot of people discover oneself to have gallbladder stone, but normally have no pain to wait for a symptom, so then muttering: "what should be done with the gall stone that has no symptom? Can you give up?" In fact, whether the gallstones need further treatment, the symptoms are not the only criteria.

　　Gallstones, also known as cholelithiasis, include gallbladder stones, bile duct stones and gallbladder, and bile duct mixed stones, among which the most commonly seen are gallstones. The most common symptom is pain in the upper abdomen or right upper abdominal costal margin, each time 15 ~ 30 minutes, can be to the right shoulder, back radiation, sometimes accompanied by nausea and vomiting. The combination of gallstones and inflammation can also result in low fever, chills, sweating and even shock.

　　Not all patients have symptoms. According to statistics, about 60% of the patients have no apparent upper abdominal pain. This mainly depends on whether the stones block gallbladder tube, merge infection, and produce mechanical stimulation to the mucosa. Number of asymptomatic gallstones are usually less cholesterol stone, large size, smooth surface, it floating within the gallbladder, suddenly stopped cystic duct or not easily fall into the common bile duct, so rarely cause acute symptoms, and may even lifelong not disease.

　　Long-term asymptomatic gallstones are generally not harmful to the human body, but when they occur in incarcerated or combined infection, they can cause symptoms and seriously affect work life. Some small gallbladder stones fall into the bile duct and into the duodenum, which can cause intestinal obstruction. Large inlays, compression of bile duct and adjacent organs to form internal fistula. Less than 0.3 cm in diameter can into the duodenum and not cause any symptoms, but after the fall into the common bile duct is easy to damage its end bile pancreatic pot belly, cause the end of common bile duct stricture, secondary common bile duct calculi and gallstone pancreatitis. The mechanical stimulation of gallstones can easily lead to bacterial infection, causing repeated inflammation of the bile duct and delaying the recovery. Cholelith disease is likely to result in gallbladder necrosis or perforation, peritonitis caused life-threatening, and cardiac arrhythmias, septic shock, liver abscess, biliary complications such as bleeding, liver failure and hepatorenal syndrome.

　　In addition, gallstones are also an important risk factor for gallbladder cancer. According to statistics, 80% of gallbladder cancer is associated with gallstones, and the incidence is positively correlated with the size of the stone and the length of the disease. According to statistics, the diameter of the stone is greater than 3 cm, and the risk of cancer is 10 times higher than 1 cm. Patients over 60 years of age with gallstones may have a 5% to 10% risk of gallbladder cancer. This may be associated with chronic calculi and chronic irritation of the gallbladder mucosa, degeneration and cancer.