Introduction – Company Background

GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.

With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.

With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.

From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.

At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.

By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.

Core Strengths in Insole Manufacturing

At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.

Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.

We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.

With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.

Customization & OEM/ODM Flexibility

GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.

Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.

With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.

Quality Assurance & Certifications

Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.

We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.

Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.

ESG-Oriented Sustainable Production

At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.

To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.

We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.

Let’s Build Your Next Insole Success Together

Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.

From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.

Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.

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Indonesia pillow OEM manufacturer

Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.

With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Breathable insole ODM development Thailand

Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.

We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Taiwan graphene sports insole ODM factory

At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Vietnam insole ODM design and production

📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.China graphene sports insole ODM

Hoplitis onosmaevae sp. nov., female (holotype). 3. Lateral view; 4. Head; 5. Clypeus and mandibles; 6. Metasoma, dorsal view; 7. Last sternum, ventral view; 8. Propodeum; 9. Inner spur of hind tibia, posterior view. Credit: Aubert et al. A new bee species, Hoplitis onosmaevae, discovered in the French Alps and parts of Turkey and Iraq, exhibits unique ecological adaptations and faces conservation challenges due to its highly specialized habitat requirements. A team of European researchers has discovered a new species of osmiine bee with an unusual geographic distribution. Hoplitis onosmaevae is currently found exclusively in the Mercantour National Park in the French Alps and disparate mountainous regions in Turkey and Northern Iraq. The distance of more than 2000 km between these areas highlights a significant biogeographic disjunction. Hoplitis onosmaevae, nesting habitat and behavior (France, Saint-Dalmas-le-Selvage, 23.6.2020, for photographs). 20. Female in buzzing position on a flower of Onosma tricerosperma subsp. fastigiata; 21. Female leaving a flower of Onosma tricerosperma subsp. fastigiata; 22. Nesting habitat with dead trunks of larch; 23. Nest entrance plugged with sand and pebbles; 24. Female near the nest entrance, which is visible at the bottom left; 25. Cross-section of nest (P = pollen provisions). Credit: Aubert et al. Described in the open-access journal Alpine Entomology, the new bee species demonstrates unique ecological characteristics such as its distinct nesting behaviour in dead wood. Presumed to only harvest pollen from Onosma species, it has a long proboscis, which is likely an adaptation to collect nectar from the long-tubed flowers of this genus. The strongly disjunct distribution of Hoplitis onosmaevae has important implications for conservation. The species likely has a very narrow ecological niche, making it highly susceptible to future changes in its habitats, for example, due to changes in agricultural practices or to climate change. Distribution map of Hoplitis onosmaevae sp. nov. Credit: Aubert et al. “The consideration of the few known populations of this species in France is very important in the conservation field,” says lead author Matthieu Aubert, freelance entomologist and member of the Observatoire des Abeilles association. “This study highlights the incredible diversity of wild bees and that we still have a lot to learn from our environment, even in western Europe,” he continues. Hoplitis onosmaevae sp. nov., foraging habitat and behaviour (France, Saint-Dalmas-le-Selvage, 23.6.2020). 15. Foraging habitat with patch of the host plant, Onosma tricerosperma subsp. fastigiata; 16. Male resting on stone between two patrolling flights, with unfolded proboscis; 17. Male resting on stone between two patrolling flights; 18. Female on a flower of Onosma tricerosperma subsp. fastigiata; 19. Female concentrating nectar with widely open mandibles. Credit: Aubert et al. The researchers emphasize the need for detailed conservation plans in the southwestern Alps to ensure the survival of Hoplitis onosmaevae, considering its highly specialized ecological niche and consequently its vulnerability to habitat changes. Their proposals for initial conservation steps can be found in the full research paper. Reference: “A new osmiine bee with a spectacular geographic disjunction: Hoplitis (Hoplitis) onosmaevae sp. nov. (Hymenoptera, Anthophila, Megachilidae)” by Matthieu Aubert, Andreas Müller and Christophe Praz, 20 March 2024, Alpine Entomology. DOI: 10.3897/alpento.8.118039

A reconstruction of the bohaiornithid Sulcavis, a close relative of Bohaiornis guoi, hunting an insect. Credit: © S. Abramowicz, Dinosaur Institute, Natural History Museum of Los Angeles County Cracking the Mystery of Enantiornithine Diets It’s hard to know what prehistoric animals’ lives were like—even answering seemingly simple questions, like what they ate, can be a challenge. Sometimes, paleontologists get lucky, and pristine fossils will preserve an animal’s stomach contents or provide other clues. In a new study in Frontiers in Earth Science, researchers investigating the fossil of a bird that lived alongside the dinosaurs got more questions than answers when they found quartz crystals in the bird’s stomach. “I would say it’s some kind of bizarre form of soft tissue preservation that we’ve never seen before,” says Jingmai O’Connor, the associate curator of fossil reptiles at Chicago’s Field Museum. “Figuring out what’s in this bird’s stomach can help us understand what it ate and what role it played in its ecosystem.” “This paper tells us that the Enantiornithes, one important clade of fossil birds, still have no direct stomach traces or evidence,” says Shumin Liu, a student at the Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences, and the paper’s first author. “I was excited, it is a breakthrough about them.” Bohaiornis guoi and the Enigmatic Stomach Crystals The fossil bird the researchers focused on is a specimen of Bohaiornis guoi. “They’re part of an early lineage of birds from the Cretaceous, about 120 million years ago,” says O’Connor, who worked on the paper while at IVPP, where Liu was her Master’s student. “They still retain teeth and claws on their hands, but they’re small, about the size of a pigeon, so they’re not particularly terrifying.” Bohaiornis was part of a group called the enantiornithines that were once the world’s most common birds; thousands of enantiornithine specimens have been found in northeastern China’s Jehol Group deposits. X-ray image of crystals in the stomach of Bohaiornis guoi. Credit: © Liu et al, IVPP. Despite the vast number of finely preserved enantiornithines, none have been preserved with traces of food in their stomachs that could tell researchers what these birds ate. “We can identify the diet and reconstruct the digestive system for all these other groups of birds found in the deposits that record the Jehol Biota, except the enantiornithines, even though you have more enantiornithines than any other group,” says O’Connor. “For these guys, we have no specimens or preserved evidence of diet, which is really weird.” In the specimen O’Connor and her colleagues examined in this new paper, though, there was a clue: a previous study pointed out the presence of small rocks in its stomach. Many living birds have an organ called a gizzard—a thick, muscular part of the stomach that helps them digest food. They swallow small rocks, called gizzard stones, and these rocks make their way to the gizzard, where they help to crush up tough food. These gizzard stones, called gastroliths, have been found in some dinosaur and bird fossils, providing clues about what those animals ate—they’ve been associated with diets of tough plant materials and seeds. But rocks in an animal’s stomach aren’t necessarily a sign that it’s using them to crush up food. Some modern birds of prey swallow rocks called rangle to help dislodge matter from their digestive tract to clean it out. And sometimes, rocks have been found near the stomach cavities of dinosaur fossils that the creature swallowed accidentally, or the stones were just coincidentally near the fossil. “You have to make a differentiation between just a gastrolith and a gastrolith that’s used as a gizzard stone,” says O’Connor. The fossil specimen of Bohaiornis with crystals in its stomach. Credit: © Liu et al, IVPP. While there’s no clear evidence of gastroliths in the enantiornithine birds, a paper published in 2015 posited that a specimen of Bohaiornis guoi contained rocks in its stomach used as rangle (gastroliths ingested by raptorial birds to clean the stomach, but not to digest food). O’Connor was skeptical; the photos of the rocks didn’t look right. Gastroliths are usually made of different kinds of rock and are slightly different colors and shapes; these rocks were all similar in composition to each other and to the fossilized bone itself. They also didn’t seem to be shaped or grouped quite right—they were too round and too scattered. “I didn’t know what they were, but I was like, they’re not gastroliths,” she says. So, she and her colleagues set out to figure out what these rocks were and compare them with gastroliths from other fossil birds and dinosaurs. Microscopy and X-rays Reveal Chalcedony, Not Gastroliths The researchers extracted a sample of the rocks in Bohaiornis’s stomach and examined them under a scanning electron microscope. They then exposed the rocks to X-rays to determine which wavelengths the rocks absorbed. Since each mineral absorbs different wavelengths, this helped the researchers narrow down what these rocks were made of. “We found that those pieces of rock that had been called gastroliths were chalcedony crystals,” says O’Connor. “Chalcedony is basically quartz crystals that grow in sedimentary rocks. There hasn’t been any evidence of this in the Jehol but there’s plenty of evidence of it within the fossil record where chalcedony crystals will form within a clamshell, or sometimes chalcedony will replace the minerals making up the bones in a fossil.” What’s more, the chalcedony was all interconnected in one thin sheet of crystal, rather than separate rocks that the bird had swallowed. Size and Weight of Crystals Don’t Fit Rangle Theory The amount of chalcedony present was wrong, too, if it were used to help with digestion. Scientific literature suggests that the rocks that birds consume as rangle account for about 3% of their body mass; since Bohaiornis was likely about 300 grams (10.6 ounces), the team would be looking for up to 9 grams (0.3 ounces) worth of rangle. O’Connor says, “We weren’t able to extract the entire sample and figure out how much it weighed, but Shumin was really clever, and she took a piece of chalcedony that weighed 3 grams (0.1 ounces), and it was huge” —way bigger than the combined size of the bits of chalcedony in Bohaiornis’s stomach. The combined evidence suggests that Bohaiornis didn’t have gastroliths to help crush food or rangle to help clean out its stomach after all. Or, at least, this specimen of Bohaiornis doesn’t contain those gastroliths. “We just have this absence of evidence, and paleontologists always say absence of evidence is not evidence of absence. But I always counter with, whoever came up with that adage never imagined having thousands of specimens that are complete and articulated, some preserving soft tissue,” says O’Connor. If Early Cretaceous enantiornithines did employ gastroliths, it’s awfully strange that none of the thousands of fossils show them. An Ongoing Paleontological Puzzle O’Connor notes that while none of the enantiornithine birds from the Jehol Formation show evidence of stomach contents, there’s one from Spain with bits of freshwater shellfish in its stomach. But the mystery of what Bohaiornis ate, and why none of the Jehol enantiornithines have anything in their stomachs, remains. “This study is important because this fossil is the one and only fossil record of Enantiornithes containing possible gastroliths, even possible real stomach traces in the Jehol. What’s more, only this clade of fossil birds don’t have stomach traces so far, whereas most other clades have these traces,” says Liu. “We’re always trying to find some evidence, and the specimens that have been suggested to fill this gap just unfortunately don’t do it,” says O’Connor. “It’s just part of the paleo game, part of science—constantly correcting. I’m happy when we don’t understand things, because it means there’s research to do, it’s exciting.” Reference: “Investigating Possible Gastroliths in a Referred Specimen of Bohaiornis guoi (Aves: Enantiornithes)” by Shumin Liu, Zhiheng Li, Alida M. Bailleul, Min Wang and Jingmai O’Connor, 19 February 2021, Frontiers in Earth Science. DOI: 10.3389/feart.2021.635727

Researchers in Japan have successfully used a nonviral piggyBac transposon system to introduce transgenes into cynomolgus monkeys, overcoming limitations of traditional virus-based methods. This breakthrough enables more precise and efficient genetic modifications in primates, opening new possibilities for modeling complex human diseases beyond the capabilities of rodent models. Credit: ASHBi/Kyoto University Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease models and advancing primate genetic engineering. Genetic engineering in non-human primates has traditionally relied on virus-based methods to deliver genes, which has posed significant limitations. In a recent breakthrough, researchers in Japan successfully introduced a transgene, a gene artificially inserted into an organism, into cynomolgus monkeys using a nonviral approach. This marks a significant advancement in primate genetic engineering. While small animal models like mice are widely used in research, they often fall short in accurately mimicking the complexity of human diseases, especially in fields such as infectious diseases and neuropsychiatric disorders. As a result, non-human primates have become critical models for biomedical research. However, genetically modifying these primates has proven difficult. Virus-based methods, for instance, require high-level biosafety facilities and are constrained by the limited capacity of viral vectors to carry large genes. Moreover, these methods lack the precision needed to select genetically modified embryos before implantation, further complicating the process. A Nonviral Alternative: The PiggyBac Transposon System To overcome these challenges, the research team sought an alternative to using viruses to carry transgenes, instead opting for a nonviral piggyBac transposon system. Transposons, which are sequences of DNA that can change positions within a genome, are valuable tools for gene transfer in genetic engineering as they can stably integrate genetic material into the host’s DNA. The piggyBac transposon system offers several advantages over traditional virus-based approaches, including greater flexibility in terms of the size of transgenes that can be carried and the ability to confirm successful modifications at the early embryo stage. This allows for more efficient embryo screening before implantation, increasing the likelihood of producing genetically modified animals that carry the desired traits. Using this approach, the team successfully generated transgenic cynomolgus monkeys, marking a major advancement in genetic engineering. In the resulting cynomolgus monkeys, there was widespread expression of fluorescent reporter genes (that is, the production of fluorescent reporter proteins based the genetic information). Red fluorescent protein was localized to cell membranes, and green fluorescent protein was localized to cell nuclei. Expression was confirmed across all tissues examined, including germ cells, demonstrating that the transgene was stably introduced. These findings suggest that the piggyBac transposon system has significant potential for creating genetically modified primates, which could be used to study human disease in ways that traditional rodent models cannot replicate. Optimizing Gene Expression for Future Applications While the transgene integration pattern was consistent across different tissues, expression levels varied. This variability underscores the need in future applications to carefully select promoters—the regulatory regions of DNA that turn on and off specific genes—based on the target tissue. For example, genes such as OCT3/4 and DDX4 play important roles in germ cell lineage differentiation, while SYN1 and THY1 are involved in Neuronal lineage differentiation. By selecting appropriate promoters for specific tissues, researchers can fine-tune gene expression to achieve the desired effects, an essential step in advancing genetic models for disease research. “Our research represents a milestone in the field of genetic engineering,” explains Dr. Tomoyuki Tsukiyama who led this project. “Our method provides a practical and efficient way to introduce transgenes into non-human primates, which we hope will unlock new insights into complex human diseases.” Looking ahead, the team plans to expand the applications of this system to include multiplex gene expression and precise transgene control, thereby allowing for more sophisticated genetic models. In addition, the researchers are exploring the potential for integrating epigenetic data about how genes are turned on and off into their work in order to better understand how gene expression is regulated at the molecular level. By refining these techniques, the researchers aim to explore disease mechanisms that remain inaccessible in rodent models and ultimately improve our understanding of complex health conditions in humans. Reference: “Non-viral generation of transgenic non-human primates via the piggyBac transposon system” by Masataka Nakaya, Chizuru Iwatani, Setsuko Tsukiyama-Fujii, Ai Mieda, Shoko Tarumoto, Taro Tsujimura, Takuya Yamamoto, Takafumi Ichikawa, Tomonori Nakamura, Ichiro Terakado, Ikuo Kawamoto, Takahiro Nakagawa, Iori Itagaki, Mitinori Saitou, Hideaki Tsuchiya and Tomoyuki Tsukiyama, 24 March 2025, Nature Communications. DOI: 10.1038/s41467-025-57365-w

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