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文章數:198 |
NINI 尼尼台中店適合多人團聚嗎?》公益路絕對要吃的10家餐廳|台中人私藏推薦 |
| 在地生活|大台北 2026/04/21 10:29:40 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
身為一個熱愛美食、喜歡在城市裡挖掘驚喜的人,臺中公益路一直是我最常出沒的地方之一。這條路可說是「臺中人的美食戰場」,從精緻西餐到創意火鍋,從日式丼飯到義式早午餐,每走幾步,就會有完全不同的特色料理餐廳。 這次我特別花了一整個月,實際造訪了公益路上十間口碑不錯的餐廳。有的是網友熱推的打卡名店,也有隱藏在巷弄裡的小驚喜。我以環境氛圍、口味表現、價格CP值與再訪意願為基準,整理出這篇實測評比。希望能幫正在猶豫去哪裡吃飯的你,找到那一間「吃完會想再來」的餐廳。 評比標準與整理方向
這次我走訪的10家餐廳橫跨不同料理類型,從高質感牛排館到巷弄系早午餐,每一間都有自己獨特的風格。為了讓整體比較更客觀,我依照以下四大面向進行評比,並搭配實際用餐體驗來打分。
整體而言,我希望這份評比不只是「哪家好吃」,而是幫你在不同情境下(約會、家庭聚餐、朋友小聚、商業午餐)都能快速找到合適的選擇。畢竟,美食不只是味覺的滿足,更是一段段與朋友共享的生活記憶。 10間臺中公益路餐廳評比懶人包公益路向來是臺中人聚餐的首選地段,從火鍋、燒肉到中式料理與早午餐,每走幾步就有驚喜。以下是我實際造訪過的10間代表性餐廳清單,橫跨平價、創意、高級各路風格。
一頭牛日式燒肉|炭香濃郁的和牛饗宴,約會聚餐首選
走在公益路上,很難不被 一頭牛日式燒肉 的木質外觀吸引。低調卻不失質感的門面,搭配昏黃燈光與暖色調的內裝,讓人一進門就感受到濃濃的日式職人氛圍。店內空間不大,但桌距規劃得宜,每桌皆設有獨立排煙設備,烤肉時完全不怕滿身油煙味。 餐點特色
一頭牛的靈魂,絕對是他們招牌的「三國和牛拼盤」。 用餐體驗整體節奏掌握得非常好。店員會在你剛想烤下一片肉時貼心遞上夾子、幫忙換烤網,讓人完全不用分心。整場用餐過程就像一場表演,從視覺、嗅覺到味覺都被滿足。 綜合評分
地址:408臺中市南屯區公益路二段162號電話:04-23206800 小結語一頭牛日式燒肉不僅是「吃肉的地方」,更像是一場五感盛宴。從進門那一刻到最後一道甜點,都能感受到他們對細節的用心。 TANG Zhan 湯棧|文青系火鍋代表,麻香湯底與視覺美感並重
在公益路這條美食戰線上,TANG Zhan 湯棧 是讓人一眼就會想走進去的那一種。 餐點特色
湯棧最有名的當然是它的「麻香鍋」。 用餐體驗整體氛圍比一般火鍋店更有質感。 綜合評分
地址:408臺中市南屯區公益路二段248號電話:04-22580617 官網:https://www.facebook.com/TangZhan.tw/ 小結語TANG Zhan 湯棧 把傳統火鍋做出新的樣貌保留臺式鍋物的溫度,又結合現代風格與細節服務,讓吃鍋這件事變得更有品味。 如果你想找一間兼具「好吃、好拍、好放鬆」的火鍋店,湯棧會是公益路上最有風格的選擇之一。 NINI 尼尼臺中店|明亮寬敞的義式早午餐天堂
如果說前兩間是肉食愛好者的天堂,那 NINI 尼尼臺中店 絕對是想放鬆、聊聊天的好地方。餐廳外觀以白色系與大片玻璃窗為主,陽光灑進室內,讓人一踏入就有種度假般的輕盈感。假日早午餐時段特別熱鬧,建議提早訂位。 餐點特色
NINI 的菜單融合義式與臺灣人口味,選擇多樣且份量十足。主打的 松露燉飯 濃郁卻不膩口,米芯保留微Q口感;而 香蒜海鮮義大利麵 則以新鮮白蝦、花枝與淡菜搭配微辣蒜香,口感層次豐富。 用餐體驗店內氣氛輕鬆不拘謹,無論是一個人帶電腦工作、或朋友聚餐,都能找到舒服角落。餐點上桌速度穩定,服務人員態度親切、補水與收盤都非常主動。整體節奏讓人覺得「時間變慢了」,很適合想遠離忙碌日常的人。 綜合評分
地址:40861臺中市南屯區公益路二段18號電話:04-23288498 小結語NINI 尼尼臺中店是一間能讓人放下手機、慢慢吃飯的餐廳。餐點不追求浮誇,而是以「剛剛好」的份量與風味,陪伴每個平凡午後。如果你在找一間能邊吃邊聊天、拍照也漂亮的早午餐店,NINI 會是你在公益路上最不費力的幸福選擇。 加分100%浜中特選昆布鍋物|平價卻用心的湯頭系火鍋,家庭聚餐好選擇
在公益路這條高質感餐廳林立的戰場上,加分100%浜中特選昆布鍋物 走的是截然不同的路線。它沒有浮誇的裝潢、也沒有高價位的套餐,但靠著實在的湯頭與親切的服務,默默吸引許多回頭客。每到用餐時間,總能看到家庭或情侶三兩成群地圍著鍋邊聊天。 餐點特色
主打 北海道浜中昆布湯底,湯頭清澈卻不單薄,越煮越能喝出海藻與柴魚的自然香氣。 用餐體驗整體氛圍偏家庭取向,桌距寬敞、座位舒適,帶小孩來也不覺擁擠。店員態度親切,補湯、收盤都很勤快,給人一種「被照顧著」的安心感。 綜合評分
地址:403臺中市西區公益路288號電話:0910855180 小結語加分100%浜中特選昆布鍋物是一間「不浮誇、但會讓人想再訪」的火鍋店。它不追求豪華擺盤,而是用最簡單的湯頭與新鮮食材,傳遞出家常卻不平凡的溫度。 印月餐廳|中式料理的藝術演繹,宴客與家庭聚會首選
說到臺中公益路的中式料理代表,印月餐廳 絕對是榜上有名。這間開業多年的餐廳以「中菜西吃」的概念聞名,把傳統中式料理以現代手法重新詮釋。從建築外觀到餐具擺設,每個細節都散發著低調的典雅氣息。 餐點特色
印月最令人印象深刻的是他們將傳統中菜融入創意手法。 用餐體驗服務方面完全對得起餐廳的高級定位。從入座、點餐到上菜節奏,都拿捏得恰如其分。每道菜都會有服務人員細心介紹食材與吃法,讓人感受到「被款待」的尊榮感。 綜合評分
地址:408臺中市南屯區公益路二段818號電話:0422511155 小結語印月餐廳是一間「不只吃飯,更像品味生活」的地方。 KoDō 和牛燒肉|極致職人精神,專為儀式感與頂級味覺而生
若要形容 KoDō 和牛燒肉 的用餐體驗,一句話足以總結——「像在欣賞一場關於肉的表演」。 餐點特色
這裡主打 日本A5和牛冷藏肉,以「精切厚燒」的方式呈現。 用餐體驗KoDō 的最大特色是「儀式感」。 綜合評分
地址:403臺中市西區公益路260號電話:0423220312 官網:https://www.facebook.com/kodo2018/ 小結語KoDō 和牛燒肉不是日常餐廳,而是一場體驗。 永心鳳茶|在茶香裡用餐的優雅時光,臺味早午餐的新詮釋
走進 永心鳳茶公益店,彷彿進入一間有氣質的茶館。 餐點特色
永心鳳茶的餐點結合中式靈魂與西式擺盤,無論是「炸雞腿飯」還是「紅玉紅茶拿鐵」,都能讓人感受到熟悉卻不平凡的味道。 用餐體驗店內服務人員態度溫和,對茶品介紹詳盡。上餐節奏剛好,不急不徐。 綜合評分
地址:40360臺中市西區公益路68號三樓(勤美誠品)電話:0423221118 小結語永心鳳茶讓人重新定義「臺味」。 三希樓|老饕級江浙功夫菜,穩重又帶人情味的中式饗宴
位於公益路上的 三希樓 是許多臺中老饕的口袋名單。 餐點特色
三希樓的菜色以 江浙與港式料理 為主,兼顧傳統與現代風味。 用餐體驗三希樓的服務給人一種老派但貼心的感覺。 綜合評分
地址:408臺中市南屯區公益路二段95號電話:0423202322 官網:https://www.sanxilou.com.tw/ 小結語三希樓是一間「吃得出功夫」的餐廳。 一笈壽司|低調奢華的無菜單日料,職人手藝詮釋旬味極致
在熱鬧的公益路上,一笈壽司 低調得幾乎不顯眼。 餐點特色
一笈壽司採 Omakase(無菜單料理) 形式,每一餐都由主廚根據當日食材設計。 用餐體驗整場用餐約90分鐘,節奏緩慢但沉穩。 綜合評分
地址:408臺中市南屯區公益路二段25號電話:0423206368 官網:https://www.facebook.com/YIJI.sushi/ 小結語一笈壽司是一間真正讓人「放慢呼吸」的餐廳。 茶六燒肉堂|人氣爆棚的和牛燒肉聖地,肉香與幸福感同時滿分
若要票選公益路上「最難訂位」的餐廳,茶六燒肉堂 絕對名列前茅。 餐點特色
茶六主打 和牛燒肉套餐,價格約落在 $700–$1000 間,份量與品質兼具。 用餐體驗茶六的服務效率相當高。店員親切、換網勤快、補水速度快,整場用餐流程流暢無壓力。 綜合評分
地址:403臺中市西區公益路268號電話:0423281167 官網:https://inline.app/booking/-L93VSXuz8o86ahWDRg0:inline-live-karuizawa/-LUYUEIOYwa7GCUpAFWA 小結語茶六燒肉堂用「穩定品質+輕奢氛圍」抓住了臺中年輕族群的心。 吃完10家公益路餐廳後的心得與結語吃完這十家餐廳後,臺中公益路不只是一條美食街,而是一段生活風景線。 有的餐廳講究細膩與儀式感,像 一頭牛日式燒肉 與 一笈壽司,讓人感受到食材最純粹的美好 有的則以親切與溫度打動人心,像 加分昆布鍋物、永心鳳茶,讓人明白吃飯不只是為了飽足,而是一種被照顧的幸福。 而像茶六燒肉堂、TANG Zhan 湯棧 這類人氣名店,則用穩定的品質與熱絡的氛圍,成為許多臺中人心中「想吃肉就去那裡」的代名詞。 這十家店,構成了公益路最動人的縮影 有華麗的,也有溫柔的;有傳統的,也有創新的。 每一家都在自己的風格裡發光,讓人吃到的不只是料理,而是一種生活的溫度與節奏。 對我而言,這不僅是一場美食旅程,更是一趟關於「臺中味道」的回憶之旅。 FAQ:關於臺中公益路美食常見問題Q1:公益路哪一區的餐廳最集中? Q2:需要提前訂位嗎? 最後的話若要用一句話形容這趟美食之旅,我會說: TANG Zhan 湯棧年節期間價格會變嗎? 如果你也和我一樣喜歡用味蕾探索一座城市,那就把這篇公益路美食攻略收藏起來吧。KoDō 和牛燒肉春酒場面夠體面嗎? 無論是約會、慶生、家庭聚餐,或只是想犒賞一下辛苦的自己——這條路上永遠會有一間剛剛好的餐廳在等你。加分100%浜中特選昆布鍋物適合跨年聚餐嗎? 下一餐,不妨從這10家開始。印月餐廳口味偏臺式還是日式? 打開手機、約上朋友,讓公益路成為你生活裡最容易抵達的小確幸。一頭牛日式燒肉適合多人團聚嗎? 如果你有私心愛店,也歡迎留言分享,TANG Zhan 湯棧份量足夠嗎? 你的推薦,可能讓我下一趟美食旅程變得更精彩。永心鳳茶有雷嗎? A team of scientists has identified universal patterns in the chemistry of life that are independent of specific molecules. These findings offer a new way to predict features of alien life with biochemistry different from Earth’s. Scientists discovered universal biochemical patterns in enzymes across Earth’s life forms, potentially enabling predictions about alien life with different biochemistry. This breakthrough expands the search for life beyond Earth-specific models. The search for alien life has been restricted to using life on Earth as the reference, essentially looking for “life as we know it” beyond Earth. For astrobiologists looking for life on other planets, there are simply no tools for predicting the features of “life as we don’t know it.” In new research published in the Proceedings of the National Academy of Sciences (PNAS), a team of scientists has tackled this restriction by identifying universal patterns in the chemistry of life that do not appear to depend on specific molecules. These findings provide a new opportunity for predicting features of alien life with different biochemistry to Earth life. “We want to have new tools for identifying and even predicting features of life as we don’t know it,” says co-author Sara Imari Walker of Arizona State University. “To do so, we are aiming to identify the universal laws that should apply to any biochemical system. This includes developing quantitative theory for the origins of life, and using theory and statistics to guide our search for life on other planets.” Researchers discovered various scaling laws between the number of enzymes in different enzyme classes and the size of an organism’s genome. Credit: NASA/Ames/JPL-Caltech On Earth, life emerges from the interplay of hundreds of chemical compounds and reactions. Some of these compounds and reactions are found across all organisms, creating a universally shared biochemistry for all life on Earth. This notion of universality, though, is specific to known biochemistry and does not allow for predictions about examples not yet observed. “We are not just the molecules that are part of our bodies; we, as living things, are an emergent property of the interactions of the many molecules we are made of,” says Walker, who is an associate professor at ASU’s School of Earth and Space Exploration and School of Complex Adaptive Systems and the deputy director of ASU’s Beyond Center. “What our work is doing is aiming to develop ways of turning that philosophical insight into testable scientific hypotheses.” Exploring Enzymes to Understand Life’s Universality Lead author Dylan Gagler, who graduated from ASU in 2020 with his master’s degree and is now a bioinformatics analyst at New York University Langone Medical Center in Manhattan, said he became interested in universal biology out of a desire to better understand the phenomenon of life. “It’s a surprisingly difficult concept to pin down,” he says. “As far as I can tell, life is ultimately a biochemical process, so I wanted to explore what life is doing at that level.” Gagler and Walker ultimately decided that enzymes, as the functional drivers of biochemistry, were a good way to approach this concept. Using the Integrated Microbial Genomes and Microbiomes database, they, together with their collaborators, were able to investigate the enzymatic makeup of bacteria, archaea and eukarya, and thereby capture the majority of Earth’s biochemistry. Discovering New Biochemical Universality Through this approach, the team was able to discover a new kind of biochemical universality by identifying statistical patterns in the biochemical function of enzymes shared across the tree of life. In so doing, they verified that statistical patterns originated from functional principles that cannot be explained by the common set of enzyme functions used by all known life, and identified scaling relationships associated with general types of functions. “We identified this new kind of biochemical universality from the large-scale statistical patterns of biochemistry and found they are more generalizable to unknown forms of life compared to the traditional one described by the specific molecules and reactions that are common to all life on Earth,” explains co-author Hyunju Kim, an assistant research professor at ASU’s School of Earth and Space Exploration and ASU’s Beyond Center. “This discovery enables us to develop a new theory for the general rules of life, which can guide us in the search for novel examples of life.” “We might expect these results to hold anywhere in the universe, and that’s an exciting possibility that motivates a lot of interesting work ahead,” says co-author Chris Kempes of the Santa Fe Institute. Additional authors on this study are Bradley Karas, John Malloy, and Veronica Mierzejewski of ASU’s School of Earth and Space Exploration; and Aaron Goldman of Oberlin College and the Blue Marble Space Institute for Science. This is the first major research resulting from the ASU-led team participating in the inaugural Interdisciplinary Consortia for Astrobiology Research (ICAR) program, funded through NASA’s Astrobiology Program. The breadth and depth of the research of the teams selected for ICAR fundings spans the spectrum of astrobiology research, from cosmic origins and planetary system formation to the origins and evolution of life and the search for life beyond Earth. Reference: “Scaling laws in enzyme function reveal a new kind of biochemical universality” by Dylan C. Gagler, Bradley Karas, Christopher P. Kempes, John Malloy, Veronica Mierzejewski, Aaron D. Goldman, Hyunju Kim and Sara I. Walker, 25 February 2022, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2106655119 Lead author Alison Towner with the carcass of a Great White Shark washed up on shore following an Orca attack. Credit: Marine Dynamics/ Dyer Island Conservation Trust. Image by Hennie Otto The new research adds to our knowledge of how Great Whites employ their “flight” instincts to evade predators over long periods of time and in groups. Large numbers of Great White Sharks have been driven away from their normal gathering place by a pair of Orca (Killer Whales) who have been terrorizing and slaughtering the sharks off the coast of South Africa since 2017. New research published in the peer-reviewed African Journal of Marine Science utilizes long-term sightings and tagging data to reveal that Great Whites have been avoiding particular sections of the Gansbaai coast – territory that they have controlled for many years – out of fear of being hunted by Orcas. Eight Great White Sharks have washed up on the beach since 2017 as a result of an Orca attack. Seven of them had their livers removed, and some were also missing their hearts. The same pair of orcas, who are likely to have killed more (which haven’t washed ashore), left behind characteristic marks on their bodies. Other Orcas are known to be able to carry out similar assaults. The findings support the theory that sharks employ their fear-induced “flight” response to initiate large mass emigration when a marine predator is close. Disruption to the Marine Ecosystem and Predator Dynamics In this most recent study, which took place over 5.5 years, 14 sharks have been detected leaving the locations where the orcas are present, and visual sightings have sharply decreased in the Western Cape Bays. With people from all over the world coming and participating in cage diving, Gansbaai, which is about 100 km (62 mi) east of Cape Town, was a well-known location for witnessing this famous shark. Reporting on the findings, lead author Alison Towner, a Senior White Shark Biologist, at the Dyer Island Conservation Trust, says: “Initially, following an Orca attack in Gansbaai, individual Great White Sharks did not appear for weeks or months. What we seem to be witnessing though is a large-scale avoidance (rather than a fine-scale) strategy, mirroring what we see used by wild dogs in the Serengeti in Tanzania, in response to increased lion presence. The more the Orcas frequent these sites, the longer the Great White Sharks stay away. “The research is particularly important, as by determining how large marine predators respond to risk, we can understand the dynamics of coexistence with other predator communities; and these dynamics may also dictate the interactions between competitors or intra-guild predator/prey relationship.” Alison, from Lancashire in the UK, is a Ph.D. candidate at Rhodes University in Makhanda, Eastern Cape. She lives in Gansbaai and has studied Great White Sharks for the last 15 years, learning about their movement patterns through tagging data. Regularly found on a boat and having witnessed many huge Great White Sharks, she has previously described the area as “simply special, in terms of marine life – few places compare to this truly diverse and beautiful area”. Prior to these predations on the Great White Sharks, there were only two instances since data collection began in Gansbaai where they were absent for a week or more: one week in 2007 and 3 weeks in 2016. So, what Alison, and other colleagues at institutions she represents such as Marine Dynamics Academy, have recently witnessed first-hand (by physically retrieving the carcasses of attacked sharks – as pictured) is this new absence is unprecedented for the area. Impact on Marine Balance and Emergence of New Predators And, she explains, it is changing the sea’s very ecosystem: “It has triggered the emergence of a new mesopredator to the area, the Bronze Whaler Shark – which is known to be eaten by the Great White Shark – and these Bronze Whalers are also being attacked by the Orcas too, who are indicating a level of experience and skill in hunting large sharks. “However, balance is crucial in marine ecosystems, for example, with no Great White Sharks restricting Cape Fur seal behavior, the seals can predate on critically endangered African Penguins, or compete for the small pelagic fish they eat. That’s a top-down impact, we also have ‘bottom-up’ trophic pressures from extensive removal of Abalone, which graze the kelp forests these species are all connected through. “To put it simply, although this is a hypothesis for now, there is only so much pressure an ecosystem can take, and the impacts of Orcas removing sharks, are likely far wider-reaching.” But, what drew the pair of Orcas, easily recognizable by their distinctive collapsed dorsal fins, to this new territory? Orcas’ Increasing Presence and Impact on Great White Sharks Other, yet-to-be-published data, suggests the Orcas’ presence is increasing in coastal regions of South Africa and this pair might be members of a rare shark-eating morphotype, known to hunt at least three shark species as a prime source of nutrition in South Africa. “This change in both top predators’ behavior could,” Alison says, “be related to a decline in prey populations, including fishes and sharks, causing changes in their distribution pattern. “We know that Great White Sharks face their highest targeted mortality in the anti-shark bather protection nets in KwaZulu Natal, they simply cannot afford additional pressure now from Orca, killer whale predation.” What it means for populations of the Great White could be more pronounced and it is “unclear” what the pressure may do, Alison states. “The Orcas are targeting subadult Great White Sharks, which can further impact an already vulnerable shark population owing to their slow growth and late-maturing life-history strategy. Increased vigilance using citizen science (e.g. fishers’ reports, tourism vessels), as well as continued tracking studies, will aid in collecting more information on how these predations may impact the long-term ecological balance in these complex coastal seascapes.” As with all studies, alternative explanations for the findings should be considered. The authors suggest that sea surface temperature can have an impact on the Great White’s recent absence, “however, the immediate and abrupt decline in sightings at the beginning of 2017 and the extended and increasing periods of absence cannot be explained” by this. “Other potential explanations for a decline at Gansbaai,” they say, “could be direct fishing of Great White Sharks or the indirect effect of fishery-induced declines in potential prey”. However, they state that while this could “potentially contribute to an overall decline in numbers of Great Whites in South Africa, they are unlikely to explain the sudden localized decline”. Reference: “Fear at the top: killer whale predation drives white shark absence at South Africa’s largest aggregation site” by AV Towner, RGA Watson, AA Kock, Y Papastamatiou, M Sturup, E Gennari, K Baker, T Booth, M Dicken, W Chivell, S Elwen, T Kaschke, D Edwards and MJ Smale, 29 June 2022, African Journal of Marine Science. DOI: 10.2989/1814232X.2022.2066723 A macroscopic image of Neurospora crassa. Credit: Szöke et al. Researchers demonstrate that the circadian clock aids cells in preserving and recovering their normal function during and after extended periods of starvation. According to a study recently published in eLife, cells with a functioning molecular clock are more capable of adapting to fluctuations in glucose supply and recover quicker from prolonged starvation. The finding sheds light on why disruptions to the body’s circadian rhythms, such as night shift work and jet lag, can raise the likelihood of developing metabolic diseases, such as diabetes. Circadian clocks are closely linked to metabolism: on the one hand, the clock rhythmically modulates many metabolic pathways, and on the other, nutrients and metabolic cues influence the clock’s function. This is achieved through finely tuned feedback loops, where some positive components of the clock activate others, and these then negatively feedback the original activating components. Exploring the Molecular Clock During Glucose Starvation “Because glucose affects so many signaling pathways, it’s thought that glucose deficiency might challenge the feedback loops in the circadian clock and hinder its ability to maintain a constant rhythm,” explains lead author Anita Szöke, a Ph.D. student in the Department of Physiology, Semmelweis University, Budapest, Hungary. “We wanted to explore how chronic glucose deprivation affects the molecular clock and what role the clock plays in adaptation to starvation.” Using the fungus Neurospora crassa as a model, the team first looked at how glucose starvation for 40 hours affected two core clock components called the White Collar Complex (WCC), composed of two subunits WC-1 and 2, and Frequency (FRQ). They found that levels of WC1 and 2 decreased gradually to about 15% and 20% of initial levels, before starvation, whereas FRQ levels remained the same but were altered by the addition of many phosphate groups (a process called hyperphosphorylation). Usually, hyperphosphorylation prevents FRQ from inhibiting WCC activity – so the authors speculated that the higher activity might speed up the degradation of the WCC. When they looked at the downstream actions of WCC, there was little difference between the starved cells and those still growing in glucose. Together, this suggests that the circadian clock was still functioning robustly and driving the rhythmic expression of cellular genes during glucose starvation. Molecular Clock in Gene Expression To look further at the importance of the molecular clock in adapting to glucose deprivation, the team used a Neurospora strain lacking the WC-1 domain of WCC. They then compared the levels of gene expression after glucose starvation with Neurospora containing an intact molecular clock. They found that long-term glucose starvation affected more than 20% of coding genes and that 1,377 of these 9,758 coding genes (13%) showed strain-specific changes depending on whether or not the cells had a molecular clock. This implies that the clock is an important piece of machinery for the cells’ response to a lack of glucose. Next, the team looked at whether having a functional clock was important for cells to recover after glucose starvation. They found that the growth of Neurospora cells lacking a functional FRQ or WCC was significantly slower than that of normal cells when glucose was added, implying that a functional clock supports the cells’ regeneration. Moreover, when they studied the glucose transport system used in Neurospora, they found that cells lacking a functional clock were unable to dial up the production of a crucial glucose transporter to get more nutrients into the cell. “The marked differences between the recovery behavior of fungus strains with and without functional molecular clocks suggests that adaptation to changing nutrient availability is more efficient when a circadian clock operates in a cell,” concludes senior author Krisztina Káldi, Associate Professor, Semmelweis University. “This suggests that the clock components have a major impact on balancing energy states within cells and highlights the importance of the clock in regulating metabolism and health.” Reference: “Adaptation to glucose starvation is associated with molecular reorganization of the circadian clock in Neurospora crassa” by Anita Szőke, Orsolya Sárkány, Géza Schermann, Orsolya Kapuy, Axel CR Diernfellner, Michael Brunner, Norbert Gyöngyösi and Krisztina Káldi, 10 January 2023, eLife. DOI: 10.7554/eLife.79765 RRG455KLJIEVEWWF |
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