Churg-Strauss syndrome (CSS)=allergic granulomatous angiitis
affects small- to medium-sized arteries and veins.
Wegener granulomatosis (WG), Churg-Strauss syndrome, and the microscopic form of periarteritis
--related vasculitic syndromes that affect medium- and small-sized vessels
--associated with antibodies to neutrophil cytoplasmic antigens (ANCAs)
(1) asthma (wheezing, expiratory rhonchi),
(2) eosinophilia of more than 10% in peripheral blood,
(3) paranasal sinusitis,
(4) pulmonary infiltrates (may be transient),
(5) histological proof of vasculitis with extravascular eosinophils
(6) mononeuritis multiplex or polyneuropathy
Corticosteroids
Cytotoxic agents