台灣第一份本土研究針對
糖尿病引起的射精障礙,進行試管嬰兒成果統計 TSRM DM
全球糖尿病的病人越來越多,
也因此導致糖尿病發病10年~15年併發糖尿病神經病變,包括男性性慾減少、射精困難、射精障礙,
根據台灣男性醫學會糖尿病引起的射精障礙分類:
(1)不射精,也就是無法勃起,更無法進行射精動作,
(2)逆行性射精,這是一種把精蟲射向膀胱,當男性高潮的時候,膀胱的括約肌會收縮,因此精蟲沒有別的選擇,只能往前衝龜頭,
但糖尿病的病人或部分癌症開刀切除的病人,前列腺附近的淋巴結有可能導致逆行性射精,
我們必需在尿裡面撈精純化精子,
(3)另外有一種射精障礙或性功能障礙是無法勃起,但可以射精,取得精蟲,這一類病人我們可以進行人工授精,沒有納入研究。
博元婦產科想要研究無射精和逆行性射精進行試管嬰兒統計,
從PUMED去搜尋,糖尿病跟射精障礙的試管嬰兒成功研究,
包含這兩種射精障礙竟然沒有文獻,
但如果是
逆行性射精,倒是有單一個案例或2.3個案例報告,
像博元婦產科把無法射精跟逆行性射精一起統計,竟然找不到相同研究文獻,
博元婦產科把這項統計發表在2015年台灣生殖醫學會年會,
請看以下的研究分析,我們發現如果可以透過副睪丸取精PESA,或取精前由喝蘇打水或口服蘇打錠鹼化身體的體質再射精,
從膀胱撈精,洗滌、離心,仍可以進行人工授精,為保險起見,全部進行ICSI單一精蟲顯微注射,
我們統計發現在
(1)不射精5位裡面3位懷孕,
(2)逆行性射精6位裡面4位懷孕,
發現這類病人只要太太低於38歲,透過人工科技還是可以一圓子望。
2015
The outcome of using assisted reproductive technologies in male infertility due to diabetic sexual dysfunction
蔡鋒博*, 陳昭雯, 林招彰, 張月嬌,陳曉青,徐慧鈴,潘孟麗,張琇媛,施俐君
Feng-Po Tsai, Chao-Wen Chen, Chao-Chang Lin, Yueh-Chiao Chang,Hsiao-Ching Chen,Hui-Ling Hsu,Meng-LI Pan,Hsiu-Yuan Chang,Li-Chun Shih,
Poyuan Women Clinic IVF Centre, Changhua Taiwan1
博元婦產科,不孕症試管嬰兒中心
Introduction:
Whilst diabetes needn’t present fertility problems, there are some conditions related to male infertility. These include erectile dysfuction, retarded ejaculation, retrograde ejaculation, anejaculation ,reduced sperm quality and hypogonadism. The initial management of patients with ejaculatory dysfunction is medical therapy. In couples who have failed medical therapy, assisted reproductive techniques using sperm harvested from either the urine or the male reproductive tract would be the ultimate option.
Materials and methods:
Here we analyzed the outcome of 11 infertile couples associated with diabetic sexual dysfunction receiving assisted reproductive technologies.
Result:
We performed 6 cycles of ICSI with spermatozoa retrieved from post-ejaculatory urine In 6 couples in which the men suffered from retrograde ejaculation. The patients had been instructed to alkalinize the urine by ingesting sodium bicarbonate before the procedure. The fertilization rate averaged 71.4%. Four clinical pregnancies were achieved. The other 5 couples with anjaculation treateda with IVF using spermatozoa retrieved via PESA. Three clinical pregnaancies were achieved.
Discussion:
The selection of the method of ART must be individualized to the needs of each couple based upon both male and female factors.
類別 / 人數 |
研究(人) |
懷孕(人) |
|
不射精症(Anejaculation) |
5 |
3 |
|
逆行性射精(Retrograde |
6 |
4 |
|
|
|
|