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文章數：84 |
 KoDō 和牛燒肉套餐划算嗎？》公益路聚餐必去名單｜10家適合各種場合 |
| 興趣嗜好｜偶像追星 2026/04/21 07:27:08 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
身為一個熱愛美食、喜歡在城市裡挖掘驚喜的人，臺中公益路一直是我最常出沒的地方之一。這條路可說是「臺中人的美食戰場」，從精緻西餐到創意火鍋，從日式丼飯到義式早午餐，每走幾步，就會有完全不同的特色料理餐廳。 這次我特別花了一整個月，實際造訪了公益路上十間口碑不錯的餐廳。有的是網友熱推的打卡名店，也有隱藏在巷弄裡的小驚喜。我以環境氛圍、口味表現、價格CP值與再訪意願為基準，整理出這篇實測評比。希望能幫正在猶豫去哪裡吃飯的你，找到那一間「吃完會想再來」的餐廳。 評比標準與整理方向
這次我走訪的10家餐廳橫跨不同料理類型，從高質感牛排館到巷弄系早午餐，每一間都有自己獨特的風格。為了讓整體比較更客觀，我依照以下四大面向進行評比，並搭配實際用餐體驗來打分。
整體而言，我希望這份評比不只是「哪家好吃」，而是幫你在不同情境下（約會、家庭聚餐、朋友小聚、商業午餐）都能快速找到合適的選擇。畢竟，美食不只是味覺的滿足，更是一段段與朋友共享的生活記憶。 10間臺中公益路餐廳評比懶人包公益路向來是臺中人聚餐的首選地段，從火鍋、燒肉到中式料理與早午餐，每走幾步就有驚喜。以下是我實際造訪過的10間代表性餐廳清單，橫跨平價、創意、高級各路風格。
一頭牛日式燒肉｜炭香濃郁的和牛饗宴，約會聚餐首選
走在公益路上，很難不被 一頭牛日式燒肉 的木質外觀吸引。低調卻不失質感的門面，搭配昏黃燈光與暖色調的內裝，讓人一進門就感受到濃濃的日式職人氛圍。店內空間不大，但桌距規劃得宜，每桌皆設有獨立排煙設備，烤肉時完全不怕滿身油煙味。 餐點特色
一頭牛的靈魂，絕對是他們招牌的「三國和牛拼盤」。 用餐體驗整體節奏掌握得非常好。店員會在你剛想烤下一片肉時貼心遞上夾子、幫忙換烤網，讓人完全不用分心。整場用餐過程就像一場表演，從視覺、嗅覺到味覺都被滿足。 綜合評分
地址：408臺中市南屯區公益路二段162號電話：04-23206800 小結語一頭牛日式燒肉不僅是「吃肉的地方」，更像是一場五感盛宴。從進門那一刻到最後一道甜點，都能感受到他們對細節的用心。 TANG Zhan 湯棧｜文青系火鍋代表，麻香湯底與視覺美感並重
在公益路這條美食戰線上，TANG Zhan 湯棧 是讓人一眼就會想走進去的那一種。 餐點特色
湯棧最有名的當然是它的「麻香鍋」。 用餐體驗整體氛圍比一般火鍋店更有質感。 綜合評分
地址：408臺中市南屯區公益路二段248號電話：04-22580617 官網：https://www.facebook.com/TangZhan.tw/ 小結語TANG Zhan 湯棧 把傳統火鍋做出新的樣貌保留臺式鍋物的溫度，又結合現代風格與細節服務，讓吃鍋這件事變得更有品味。 如果你想找一間兼具「好吃、好拍、好放鬆」的火鍋店，湯棧會是公益路上最有風格的選擇之一。 NINI 尼尼臺中店｜明亮寬敞的義式早午餐天堂
如果說前兩間是肉食愛好者的天堂，那 NINI 尼尼臺中店 絕對是想放鬆、聊聊天的好地方。餐廳外觀以白色系與大片玻璃窗為主，陽光灑進室內，讓人一踏入就有種度假般的輕盈感。假日早午餐時段特別熱鬧，建議提早訂位。 餐點特色
NINI 的菜單融合義式與臺灣人口味，選擇多樣且份量十足。主打的 松露燉飯 濃郁卻不膩口，米芯保留微Q口感；而 香蒜海鮮義大利麵 則以新鮮白蝦、花枝與淡菜搭配微辣蒜香，口感層次豐富。 用餐體驗店內氣氛輕鬆不拘謹，無論是一個人帶電腦工作、或朋友聚餐，都能找到舒服角落。餐點上桌速度穩定，服務人員態度親切、補水與收盤都非常主動。整體節奏讓人覺得「時間變慢了」，很適合想遠離忙碌日常的人。 綜合評分
地址：40861臺中市南屯區公益路二段18號電話：04-23288498 小結語NINI 尼尼臺中店是一間能讓人放下手機、慢慢吃飯的餐廳。餐點不追求浮誇，而是以「剛剛好」的份量與風味，陪伴每個平凡午後。如果你在找一間能邊吃邊聊天、拍照也漂亮的早午餐店，NINI 會是你在公益路上最不費力的幸福選擇。 加分100%浜中特選昆布鍋物｜平價卻用心的湯頭系火鍋，家庭聚餐好選擇
在公益路這條高質感餐廳林立的戰場上，加分100%浜中特選昆布鍋物 走的是截然不同的路線。它沒有浮誇的裝潢、也沒有高價位的套餐，但靠著實在的湯頭與親切的服務，默默吸引許多回頭客。每到用餐時間，總能看到家庭或情侶三兩成群地圍著鍋邊聊天。 餐點特色
主打 北海道浜中昆布湯底，湯頭清澈卻不單薄，越煮越能喝出海藻與柴魚的自然香氣。 用餐體驗整體氛圍偏家庭取向，桌距寬敞、座位舒適，帶小孩來也不覺擁擠。店員態度親切，補湯、收盤都很勤快，給人一種「被照顧著」的安心感。 綜合評分
地址：403臺中市西區公益路288號電話：0910855180 小結語加分100%浜中特選昆布鍋物是一間「不浮誇、但會讓人想再訪」的火鍋店。它不追求豪華擺盤，而是用最簡單的湯頭與新鮮食材，傳遞出家常卻不平凡的溫度。 印月餐廳｜中式料理的藝術演繹，宴客與家庭聚會首選
說到臺中公益路的中式料理代表，印月餐廳 絕對是榜上有名。這間開業多年的餐廳以「中菜西吃」的概念聞名，把傳統中式料理以現代手法重新詮釋。從建築外觀到餐具擺設，每個細節都散發著低調的典雅氣息。 餐點特色
印月最令人印象深刻的是他們將傳統中菜融入創意手法。 用餐體驗服務方面完全對得起餐廳的高級定位。從入座、點餐到上菜節奏，都拿捏得恰如其分。每道菜都會有服務人員細心介紹食材與吃法，讓人感受到「被款待」的尊榮感。 綜合評分
地址：408臺中市南屯區公益路二段818號電話：0422511155 小結語印月餐廳是一間「不只吃飯，更像品味生活」的地方。 KoDō 和牛燒肉｜極致職人精神，專為儀式感與頂級味覺而生
若要形容 KoDō 和牛燒肉 的用餐體驗，一句話足以總結——「像在欣賞一場關於肉的表演」。 餐點特色
這裡主打 日本A5和牛冷藏肉，以「精切厚燒」的方式呈現。 用餐體驗KoDō 的最大特色是「儀式感」。 綜合評分
地址：403臺中市西區公益路260號電話：0423220312 官網：https://www.facebook.com/kodo2018/ 小結語KoDō 和牛燒肉不是日常餐廳，而是一場體驗。 永心鳳茶｜在茶香裡用餐的優雅時光，臺味早午餐的新詮釋
走進 永心鳳茶公益店，彷彿進入一間有氣質的茶館。 餐點特色
永心鳳茶的餐點結合中式靈魂與西式擺盤，無論是「炸雞腿飯」還是「紅玉紅茶拿鐵」，都能讓人感受到熟悉卻不平凡的味道。 用餐體驗店內服務人員態度溫和，對茶品介紹詳盡。上餐節奏剛好，不急不徐。 綜合評分
地址：40360臺中市西區公益路68號三樓(勤美誠品)電話：0423221118 小結語永心鳳茶讓人重新定義「臺味」。 三希樓｜老饕級江浙功夫菜，穩重又帶人情味的中式饗宴
位於公益路上的 三希樓 是許多臺中老饕的口袋名單。 餐點特色
三希樓的菜色以 江浙與港式料理 為主，兼顧傳統與現代風味。 用餐體驗三希樓的服務給人一種老派但貼心的感覺。 綜合評分
地址：408臺中市南屯區公益路二段95號電話：0423202322 官網：https://www.sanxilou.com.tw/ 小結語三希樓是一間「吃得出功夫」的餐廳。 一笈壽司｜低調奢華的無菜單日料，職人手藝詮釋旬味極致
在熱鬧的公益路上，一笈壽司 低調得幾乎不顯眼。 餐點特色
一笈壽司採 Omakase（無菜單料理） 形式，每一餐都由主廚根據當日食材設計。 用餐體驗整場用餐約90分鐘，節奏緩慢但沉穩。 綜合評分
地址：408臺中市南屯區公益路二段25號電話：0423206368 官網：https://www.facebook.com/YIJI.sushi/ 小結語一笈壽司是一間真正讓人「放慢呼吸」的餐廳。 茶六燒肉堂｜人氣爆棚的和牛燒肉聖地，肉香與幸福感同時滿分
若要票選公益路上「最難訂位」的餐廳，茶六燒肉堂 絕對名列前茅。 餐點特色
茶六主打 和牛燒肉套餐，價格約落在 $700–$1000 間，份量與品質兼具。 用餐體驗茶六的服務效率相當高。店員親切、換網勤快、補水速度快，整場用餐流程流暢無壓力。 綜合評分
地址：403臺中市西區公益路268號電話：0423281167 官網：https://inline.app/booking/-L93VSXuz8o86ahWDRg0:inline-live-karuizawa/-LUYUEIOYwa7GCUpAFWA 小結語茶六燒肉堂用「穩定品質＋輕奢氛圍」抓住了臺中年輕族群的心。 吃完10家公益路餐廳後的心得與結語吃完這十家餐廳後，臺中公益路不只是一條美食街，而是一段生活風景線。 有的餐廳講究細膩與儀式感，像 一頭牛日式燒肉 與 一笈壽司，讓人感受到食材最純粹的美好 有的則以親切與溫度打動人心，像 加分昆布鍋物、永心鳳茶，讓人明白吃飯不只是為了飽足，而是一種被照顧的幸福。 而像茶六燒肉堂、TANG Zhan 湯棧 這類人氣名店，則用穩定的品質與熱絡的氛圍，成為許多臺中人心中「想吃肉就去那裡」的代名詞。 這十家店，構成了公益路最動人的縮影 有華麗的，也有溫柔的；有傳統的，也有創新的。 每一家都在自己的風格裡發光，讓人吃到的不只是料理，而是一種生活的溫度與節奏。 對我而言，這不僅是一場美食旅程，更是一趟關於「臺中味道」的回憶之旅。 FAQ：關於臺中公益路美食常見問題Q1：公益路哪一區的餐廳最集中？ Q2：需要提前訂位嗎？ 最後的話若要用一句話形容這趟美食之旅，我會說： 印月餐廳春酒活動適合在這裡辦嗎？ 如果你也和我一樣喜歡用味蕾探索一座城市，那就把這篇公益路美食攻略收藏起來吧。KoDō 和牛燒肉清淡口味適合嗎？ 無論是約會、慶生、家庭聚餐，或只是想犒賞一下辛苦的自己——這條路上永遠會有一間剛剛好的餐廳在等你。茶六燒肉堂食材新鮮嗎？ 下一餐，不妨從這10家開始。一笈壽司有什麼推薦搭配？ 打開手機、約上朋友，讓公益路成為你生活裡最容易抵達的小確幸。一頭牛日式燒肉有生日驚喜或畫盤嗎？ 如果你有私心愛店，也歡迎留言分享，印月餐廳小孩適合去嗎？ 你的推薦，可能讓我下一趟美食旅程變得更精彩。三希樓再訪意願高嗎？ A recent study suggests that the primary components of life on Earth may have originated from solar eruptions. The research demonstrated that solar particles colliding with gases in Earth’s primitive atmosphere could produce amino acids and carboxylic acids, the fundamental elements of proteins and organic life. Using data from NASA’s Kepler mission, researchers proposed that energetic particles from the sun, during its early superflare stage, would regularly interact with our atmosphere, triggering essential chemical reactions. Experimental replications indicated that solar particles appear to be a more efficient energy source than lightning for the formation of amino acids and carboxylic acids. Credit: NASA/Goddard Space Flight Center A new study posits that the earliest building blocks of life on Earth, namely amino acids and carboxylic acids, may have been formed due to solar eruptions. The research suggests that energetic particles from the sun during its early stages, colliding with Earth’s primitive atmosphere, could have efficiently catalyzed essential chemical reactions, thus challenging the traditional “warm little pond” theory. The first building blocks of life on Earth may have formed thanks to eruptions from our Sun, a new study finds. A series of chemical experiments show how solar particles, colliding with gases in Earth’s early atmosphere, can form amino acids and carboxylic acids, the basic building blocks of proteins and organic life. The findings were published in the journal Life. To understand the origins of life, many scientists try to explain how amino acids, the raw materials from which proteins and all cellular life, were formed. The best-known proposal originated in the late 1800s as scientists speculated that life might have begun in a “warm little pond”: A soup of chemicals, energized by lightning, heat, and other energy sources, that could mix together in concentrated amounts to form organic molecules. Artist’s concept of Early Earth. Credit: NASA In 1953, Stanley Miller of the University of Chicago tried to recreate these primordial conditions in the lab. Miller filled a closed chamber with methane, ammonia, water, and molecular hydrogen – gases thought to be prevalent in Earth’s early atmosphere – and repeatedly ignited an electrical spark to simulate lightning. A week later, Miller and his graduate advisor Harold Urey analyzed the chamber’s contents and found that 20 different amino acids had formed. “That was a big revelation,” said Vladimir Airapetian, a stellar astrophysicist at NASA’s Goddard Space Flight Center in Greenbelt, Maryland, and coauthor of the new paper. “From the basic components of early Earth’s atmosphere, you can synthesize these complex organic molecules.” But the last 70 years have complicated this interpretation. Scientists now believe ammonia (NH3) and methane (CH4) were far less abundant; instead, Earth’s air was filled with carbon dioxide (CO2) and molecular nitrogen (N2), which require more energy to break down. These gases can still yield amino acids, but in greatly reduced quantities. Seeking alternative energy sources, some scientists pointed to shockwaves from incoming meteors. Others cited solar ultraviolet radiation. Airapetian, using data from NASA’s Kepler mission, pointed to a new idea: energetic particles from our Sun. Kepler observed far-off stars at different stages in their lifecycle, but its data provides hints about our Sun’s past. In 2016, Airapetian published a study suggesting that during Earth’s first 100 million years, the Sun was about 30% dimmer. But solar “superflares” – powerful eruptions we only see once every 100 years or so today – would have erupted once every 3-10 days. These superflares launch near-light speed particles that would regularly collide with our atmosphere, kickstarting chemical reactions. Energy from our young Sun – 4 billion years ago – aided in creating molecules in Earth’s atmosphere that allowed it to warm up enough to incubate life. Credit: NASA’s Goddard Space Flight Center/Genna Duberstein “As soon as I published that paper, the team from the Yokohama National University from Japan contacted me,” Airapetian said. Dr. Kobayashi, a professor of chemistry there, had spent the last 30 years studying prebiotic chemistry. He was trying to understand how galactic cosmic rays – incoming particles from outside our solar system – could have affected early Earth’s atmosphere. “Most investigators ignore galactic cosmic rays because they require specialized equipment, like particle accelerators,” Kobayashi said. “I was fortunate enough to have access to several of them near our facilities.” Minor tweaks to Kobayashi’s experimental setup could put Airapetian’s ideas to the test. Proton Power vs. Lightning Energy Airapetian, Kobayashi, and their collaborators created a mixture of gases matching early Earth’s atmosphere as we understand it today. They combined carbon dioxide, molecular nitrogen, water, and a variable amount of methane. (The methane proportion in Earth’s early atmosphere is uncertain but thought to be low.) They shot the gas mixtures with protons (simulating solar particles) or ignited them with spark discharges (simulating lightning), replicating the Miller-Urey experiment for comparison. As long as the methane proportion was over 0.5%, the mixtures shot by protons (solar particles) produced detectable amounts of amino acids and carboxylic acids. But the spark discharges (lightning) required about a 15% methane concentration before any amino acids formed at all. “And even at 15% methane, the production rate of the amino acids by lightning is a million times less than by protons,” Airapetian added. Protons also tended to produce more carboxylic acids (a precursor of amino acids) than those ignited by spark discharges. A close up of a solar eruption, including a solar flare, a coronal mass ejection, and a solar energetic particle event. Credit: NASA’s Goddard Space Flight Center All else being equal, solar particles appear to be a more efficient energy source than lightning. But all else likely wasn’t equal, Airapetian suggested. Miller and Urey assumed that lightning was just as common at the time of the “warm little pond” as it is today. But lightning, which comes from thunderclouds formed by rising warm air, would have been rarer under a 30% dimmer Sun. “During cold conditions you never have lightning, and early Earth was under a pretty faint Sun,” Airapetian said. “That’s not saying that it couldn’t have come from lightning, but lightning seems less likely now, and solar particles seems more likely.” These experiments suggest our active young Sun could have catalyzed the precursors of life more easily, and perhaps earlier, than previously assumed. Reference: “Formation of Amino Acids and Carboxylic Acids in Weakly Reducing Planetary Atmospheres by Solar Energetic Particles from the Young Sun” by Kensei Kobayashi Jun-ichi Ise, Ryohei Aoki, Miei Kinoshita, Koki Naito, Takumi Udo, Bhagawati Kunwar, Jun-ichi Takahashi, Hiromi Shibata, Hajime Mita, Hitoshi Fukuda, Yoshiyuki Oguri, Kimitaka Kawamura, Yoko Kebukawa and Vladimir S. Airapetian, 28 April 2023, Life. DOI: 10.3390/life13051103 Mitochondria are now known to not only generate energy but also produce essential cellular materials, adapting uniquely to stress, which sheds light on cancer survival tactics and aging processes. Credit: SciTechDaily.com In an intriguing revelation from recent research, mitochondria have been shown not only to power the cell but also to manufacture essential cellular building blocks, balancing these roles, especially under stress. Scientists discovered a dynamic division of labor within mitochondria, resulting in one group focused on generating energy and another on producing structural components. This breakthrough provides profound insights into cancer’s survival strategies and potentially aging-related tissue regeneration. Beyond Energy: Building Blocks of Life Many of us recall learning in high school biology that mitochondria are the cell’s “power plants.” These small, bean-shaped structures convert nutrients from food into ATP, often described as the cell’s “energy currency.” Cells use this energy for essential tasks, such as encoding memories in nerve cells or detoxifying chemicals in liver cells. While this description is accurate, it tells only part of the story. Beyond energy, cells also need building blocks — the raw materials required to replicate their components. These building blocks ensure that as cells grow and divide, each new cell inherits a complete and equal set of parts. This series of images of the same visual field shows mitochondria with the P5CS enzyme labeled green and mitochondria with an ATP-related enzyme in purple. The two populations are clearly distinct. Credit: Memorial Sloan Kettering Cancer Center Mitochondrial Control Over Cellular Building Blocks For many years, it was not clear where in the cell these building blocks are made. But over the past decade, scientists have learned that mitochondria control this process too. Instead of using nutrients to make ATP, mitochondria can use them to make the cellular building blocks that will form DNA, new proteins, and new cell membranes. How do mitochondria choose which of these two opposing paths to take? “That was the question we set out to answer,” says Craig Thompson, MD, a member of the Cancer Biology and Genetics Program in the Sloan Kettering Institute at Memorial Sloan Kettering Cancer Center (MSK) and the senior author of a new paper published recently in Nature. “How do mitochondria balance these two essential functions that they do for all cells in our body?” Dr. Craig Thompson of MSK’s Sloan Kettering Institute is the senior author of a new paper, published in ‘Nature,’ that shows how mitochondria form two distinct subpopulations under stress. Credit: Memorial Sloan Kettering Cancer Center How Cells Survive Under Stress Under typical circumstances, he says, it’s easy for cells to square their balance sheets. When nutrients are plentiful — when our cells are getting all the nutrients they need and then some — cells can use those nutrients to make an adequate supply of ATP and also to make enough cellular building blocks for growth and division. But what happens during times of stress, when nutrients are scarce and demand for both ATP and cellular building blocks is high? No one knew the answer to that question. Mitochondrial Specialization in Stressful Conditions To appreciate the dilemma a cell faces, Dr. Thompson says, consider what happens when you cut yourself. “The blood starts to pour out, and with it the nutrients that normally sustain the tissue. The cells are now in a stressful situation. They urgently need ATP to spend on the healing process and they also urgently need new supplies to repair the wounded tissue. How the cell decides between these competing demands hasn’t been clear.” In their new paper, Dr. Thompson and his colleagues show in exquisite detail how mitochondria tackle this vexing problem. Through a dramatic and dynamic process of physical and chemical transformation, mitochondria form distinct subpopulations that are specialized for satisfying each of the competing demands. The end result is an almost perfect division of labor, with one subpopulation outfitted with the machinery for making ATP, and one subpopulation outfitted with the machinery for building new cell structures. The new findings not only answer a fundamental question about cell biology, they have direct implications for understanding cancer — the epitome of a stressful biological event. An Unexpected Approach to Mitochondrial Functions Dr. Thompson and his colleagues, led by Keunwoo Ryu, PhD, a postdoctoral fellow in the lab, started by asking what would happen if they put cells in a stressful situation, where, for example, there is a low amount of the nutrient glucose and simultaneously a high demand for ATP. You might suspect that the cells would favor making ATP at the expense of making cellular building blocks. That is not, however, what the researchers found. “The increased demand for ATP didn’t in any way compromise the cells’ ability to make other molecules for growth,” Dr. Thompson says. That was a very odd finding, one that seemed to “break the laws of thermodynamics,” he adds. It would be as if a baker started with the ingredients to make one 12-inch apple pie but at the end of cooking, had two 12-inch pies. That told the scientists that something very unusual was going on. Enzymatic Control and Mitochondrial Segregation One clue to the mystery of how mitochondria can perform two functions at once came from looking at which enzymes the two different pathways have in common. They found only one: an enzyme called P5CS. “P5CS is a kind of linchpin protein that is necessary to make the judgment between these two pathways,” Dr. Thompson explains. When the team looked in more detail at what P5CS was doing in the stressed-out cells, they saw that individual P5CS enzymes had joined together to make long filaments. But curiously, the filaments formed in only one subpopulation of mitochondria; in the other, they were absent. The subpopulation of mitochondria with the P5CS filaments were noticeably different in other ways. Typically, in mitochondria that can make ATP, the inner membrane of the mitochondria forms intricate folded structures called cristae, which are often visible in the mitochondria shown in textbooks. But in the mitochondria rich with P5CS, the cristae were absent. “It could be that these mitochondrial changes fuel how cancer cells acquire the ability to metastasize, or spread.” Craig Thompson, MD Sloan Kettering Institute Upon further probing, it became clear that the two subpopulations had completely segregated their roles, with one population becoming streamlined for just making ATP and one population becoming specialized for making new cellular building blocks. An essential upshot of this division of labor is that each subpopulation got better at doing its job, which helps explain why those original stressed-out cells were able to make both enough ATP and enough building blocks to survive and grow in the stressful conditions. Mitochondrial Dynamics and Cancer Implications But how do the two distinct subpopulations come about in the first place? Here’s where the story takes another surprising turn. Scientists have known for decades that mitochondria are highly dynamic organelles. They go through fusion and fission events, in which individual mitochondria join together and then split apart, over and over again. Scientists have hypothesized that the fusion and fission events are necessary to recycle the components of mitochondria damaged from the highly demanding process of ATP generation. That may be true. However, this new study shows that the fusion and fission process is also required to segregate the filaments of P5CS into one subpopulation and the ATP-making machinery into the other. “That was a surprise,” Dr. Thompson says. “I believe this is the first time anyone has shown that mitochondrial fusion and fission are necessary to separate functions of mitochondria into subpopulations.” Cancer and Mitochondrial Changes Why is this relevant to cancer? Well, as anyone who works in the field knows, cancer cells are able to survive in stressful conditions that typically kill normal cells. For example, cancer cells can survive in the very center of the tumor where nutrients and oxygen are scarce. No ordinary cell can do that. To see if the mitochondrial changes were happening in the context of cancer, Dr. Thompson and his colleagues looked at tissue samples of pancreatic cancer, one of the most aggressive cancers. Sure enough, the tumors had developed the discrete subpopulations of mitochondria, while the surrounding normal tissue had not. “These mitochondrial changes seem to be driving cancer progression, at least in pancreatic ductal adenocarcinoma,” Dr. Thompson says. His team is now looking to see if this discovery holds for other types of cancers, as well. They also want to investigate just how these mitochondrial changes might underlie cancer progression. “It could be that they fuel how cancer cells acquire the ability to metastasize, or spread,” he says. There’s even a possible connection to aging. “We think that understanding these mitochondrial dynamics will be critical for our understanding of how we might facilitate tissue repair and tissue regeneration as we age,” says Dr. Thompson. “When we see these mitochondrial changes, is that a sign that a tissue is under stress? We’re exploring that idea as well.” Reference: “Cellular ATP demand creates metabolically distinct subpopulations of mitochondria” by Keun Woo Ryu, Tak Shun Fung, Daphne C. Baker, Michelle Saoi, Jinsung Park, Christopher A. Febres-Aldana, Rania G. Aly, Ruobing Cui, Anurag Sharma, Yi Fu, Olivia L. Jones, Xin Cai, H. Amalia Pasolli, Justin R. Cross, Charles M. Rudin and Craig B. Thompson, 6 November 2024, Nature. DOI: 10.1038/s41586-024-08146-w This study was supported financially by the Hunter Douglas Fellowship in Breast Cancer Research, the BRIA Postdoctoral Researcher Innovation Grant, and the National Cancer Institute (grants R35 CA263816, P30 CA008748 and R35 CA283988). Quercus robur was first introduced into South Africa in 1656. Today it is one of the most widespread and recognized trees in the South African landscape, such as the centuries-old oak trees lining the streets of Stellenbosch (also known as Eikestad or Oak City). But these centuries-old trees are also the most susceptible to infections and pests such as the polyphagous shot hole borer. Credit: Christiaan Gildenhuys The nearly 400-year-old history of oaks in South Africa may be coming to an end, forever changing the treescape of towns and cities such as Cape Town, George, Paarl, Stellenbosch, and Swellendam. In a research paper published in the South African Journal of Botany, ecologists from the Centre for Invasion Biology (CIB) at Stellenbosch University’s School for Climate Studies, traced the history of the introduction of the genus Quercus into South Africa, as well as its current status and the factors that are changing its distribution across our landscapes. Christiaan Gildenhuys, a postgraduate student in SU’s Department of Botany and Zoology and first author on the article, says the first written record of English oak (Quercus robur), dates to 1656, reportedly introduced under the authority of Jan van Riebeek himself: “Dozens of other oak species were introduced to the Cape of Good Hope by early Dutch settlers and the British colonial government. Many oaks were subsequently widely cultivated across the country and have since become one of the most widespread and recognized tree genera in South Africa today,” he explains. But now the species may have arrived at a crossroads. The Threat of Disease and Invasive Species Gildenhuys found that three oak species – English oak, Pin oak, and Cork oak – have become invasive along riverbanks and the urban-wildland interface in Stellenbosch and Cape Town. These oaks do not cause major problems as invaders now but may do so in the future. At the same time, many species (including the most widespread species, Q. robur or English oak) are highly susceptible to diseases and invasive beetles such as the polyphagous shot hole borer: “Not only does this mean that many century-old oaks are at risk, but it also means that infected trees must be removed before the infestation spreads further,” says Gildenhuys. The oak-lined streets of historical towns such as Stellenbosch in South Africa (the second oldest town in South Africa after Cape Town) are set to change over the next decade. These centuries-old oak trees are particularly susceptible to the onslaught of the Polyphagous shot hole borer. Credit: Christiaan Gildenhuys Prof. Dave Richardson, an ecologist at CIB and co-author, says the story of oaks in South Africa is a classic example of how global change is rapidly changing the roles and perspectives of species in urban areas. “We must accept that the potential impact of the polyphagous shot hole borer is a game changer. As a result of this invasion, the treescapes of many towns in South Africa are going to change rather radically. Landowners and authorities who may decide to replace infected Q. robur trees with less susceptible tree species must also consider the potential negative impacts of these species,” he explains The ideal would be to replace the infected trees with indigenous species which are less susceptible to pests and diseases such as the PSHB. However, people’s attachments to their oak-lined streets may inhibit replacement efforts and induce conflicts between management and stakeholders, he warns. Prof. Guy Midgley, interim director of the School for Climate Studies, says trees make a vital contribution to lessening the impact of climate change by reducing heat stress in urban areas. On the other hand, the way thousands of diseased trees are disposed of may significantly impact carbon emissions. Adding fuel to the fire is the debate about the cultural value of oaks in general. In one sector of South African society, these centuries-old trees are celebrated as part of our cultural heritage. In another sector, they are regarded as unwanted relics from a colonial past. Reference: “The genus Quercus (Fagaceae) in South Africa: Introduction history, current status, and invasion ecology” by Christiaan P. Gildenhuys, Luke J. Potgieter and David M. Richardson, 17 February 2024, South African Journal of Botany. DOI: 10.1016/j.sajb.2024.01.066 The study was funded by the Universiteit Stellenbosch and the Natural Sciences and Engineering Research Council of Canada. RRG455KLJIEVEWWF |
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