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文章數：97 |
 加分100%浜中特選昆布鍋物節慶時段會不會太難訂位？》台中公益路美食特輯｜10家真實體驗分享 |
| 時事評論｜政治 2026/04/22 03:31:10 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
身為一個熱愛美食、喜歡在城市裡挖掘驚喜的人，臺中公益路一直是我最常出沒的地方之一。這條路可說是「臺中人的美食戰場」，從精緻西餐到創意火鍋，從日式丼飯到義式早午餐，每走幾步，就會有完全不同的特色料理餐廳。 這次我特別花了一整個月，實際造訪了公益路上十間口碑不錯的餐廳。有的是網友熱推的打卡名店，也有隱藏在巷弄裡的小驚喜。我以環境氛圍、口味表現、價格CP值與再訪意願為基準，整理出這篇實測評比。希望能幫正在猶豫去哪裡吃飯的你，找到那一間「吃完會想再來」的餐廳。 評比標準與整理方向
這次我走訪的10家餐廳橫跨不同料理類型，從高質感牛排館到巷弄系早午餐，每一間都有自己獨特的風格。為了讓整體比較更客觀，我依照以下四大面向進行評比，並搭配實際用餐體驗來打分。
整體而言，我希望這份評比不只是「哪家好吃」，而是幫你在不同情境下（約會、家庭聚餐、朋友小聚、商業午餐）都能快速找到合適的選擇。畢竟，美食不只是味覺的滿足，更是一段段與朋友共享的生活記憶。 10間臺中公益路餐廳評比懶人包公益路向來是臺中人聚餐的首選地段，從火鍋、燒肉到中式料理與早午餐，每走幾步就有驚喜。以下是我實際造訪過的10間代表性餐廳清單，橫跨平價、創意、高級各路風格。
一頭牛日式燒肉｜炭香濃郁的和牛饗宴，約會聚餐首選
走在公益路上，很難不被 一頭牛日式燒肉 的木質外觀吸引。低調卻不失質感的門面，搭配昏黃燈光與暖色調的內裝，讓人一進門就感受到濃濃的日式職人氛圍。店內空間不大，但桌距規劃得宜，每桌皆設有獨立排煙設備，烤肉時完全不怕滿身油煙味。 餐點特色
一頭牛的靈魂，絕對是他們招牌的「三國和牛拼盤」。 用餐體驗整體節奏掌握得非常好。店員會在你剛想烤下一片肉時貼心遞上夾子、幫忙換烤網，讓人完全不用分心。整場用餐過程就像一場表演，從視覺、嗅覺到味覺都被滿足。 綜合評分
地址：408臺中市南屯區公益路二段162號電話：04-23206800 小結語一頭牛日式燒肉不僅是「吃肉的地方」，更像是一場五感盛宴。從進門那一刻到最後一道甜點，都能感受到他們對細節的用心。 TANG Zhan 湯棧｜文青系火鍋代表，麻香湯底與視覺美感並重
在公益路這條美食戰線上，TANG Zhan 湯棧 是讓人一眼就會想走進去的那一種。 餐點特色
湯棧最有名的當然是它的「麻香鍋」。 用餐體驗整體氛圍比一般火鍋店更有質感。 綜合評分
地址：408臺中市南屯區公益路二段248號電話：04-22580617 官網：https://www.facebook.com/TangZhan.tw/ 小結語TANG Zhan 湯棧 把傳統火鍋做出新的樣貌保留臺式鍋物的溫度，又結合現代風格與細節服務，讓吃鍋這件事變得更有品味。 如果你想找一間兼具「好吃、好拍、好放鬆」的火鍋店，湯棧會是公益路上最有風格的選擇之一。 NINI 尼尼臺中店｜明亮寬敞的義式早午餐天堂
如果說前兩間是肉食愛好者的天堂，那 NINI 尼尼臺中店 絕對是想放鬆、聊聊天的好地方。餐廳外觀以白色系與大片玻璃窗為主，陽光灑進室內，讓人一踏入就有種度假般的輕盈感。假日早午餐時段特別熱鬧，建議提早訂位。 餐點特色
NINI 的菜單融合義式與臺灣人口味，選擇多樣且份量十足。主打的 松露燉飯 濃郁卻不膩口，米芯保留微Q口感；而 香蒜海鮮義大利麵 則以新鮮白蝦、花枝與淡菜搭配微辣蒜香，口感層次豐富。 用餐體驗店內氣氛輕鬆不拘謹，無論是一個人帶電腦工作、或朋友聚餐，都能找到舒服角落。餐點上桌速度穩定，服務人員態度親切、補水與收盤都非常主動。整體節奏讓人覺得「時間變慢了」，很適合想遠離忙碌日常的人。 綜合評分
地址：40861臺中市南屯區公益路二段18號電話：04-23288498 小結語NINI 尼尼臺中店是一間能讓人放下手機、慢慢吃飯的餐廳。餐點不追求浮誇，而是以「剛剛好」的份量與風味，陪伴每個平凡午後。如果你在找一間能邊吃邊聊天、拍照也漂亮的早午餐店，NINI 會是你在公益路上最不費力的幸福選擇。 加分100%浜中特選昆布鍋物｜平價卻用心的湯頭系火鍋，家庭聚餐好選擇
在公益路這條高質感餐廳林立的戰場上，加分100%浜中特選昆布鍋物 走的是截然不同的路線。它沒有浮誇的裝潢、也沒有高價位的套餐，但靠著實在的湯頭與親切的服務，默默吸引許多回頭客。每到用餐時間，總能看到家庭或情侶三兩成群地圍著鍋邊聊天。 餐點特色
主打 北海道浜中昆布湯底，湯頭清澈卻不單薄，越煮越能喝出海藻與柴魚的自然香氣。 用餐體驗整體氛圍偏家庭取向，桌距寬敞、座位舒適，帶小孩來也不覺擁擠。店員態度親切，補湯、收盤都很勤快，給人一種「被照顧著」的安心感。 綜合評分
地址：403臺中市西區公益路288號電話：0910855180 小結語加分100%浜中特選昆布鍋物是一間「不浮誇、但會讓人想再訪」的火鍋店。它不追求豪華擺盤，而是用最簡單的湯頭與新鮮食材，傳遞出家常卻不平凡的溫度。 印月餐廳｜中式料理的藝術演繹，宴客與家庭聚會首選
說到臺中公益路的中式料理代表，印月餐廳 絕對是榜上有名。這間開業多年的餐廳以「中菜西吃」的概念聞名，把傳統中式料理以現代手法重新詮釋。從建築外觀到餐具擺設，每個細節都散發著低調的典雅氣息。 餐點特色
印月最令人印象深刻的是他們將傳統中菜融入創意手法。 用餐體驗服務方面完全對得起餐廳的高級定位。從入座、點餐到上菜節奏，都拿捏得恰如其分。每道菜都會有服務人員細心介紹食材與吃法，讓人感受到「被款待」的尊榮感。 綜合評分
地址：408臺中市南屯區公益路二段818號電話：0422511155 小結語印月餐廳是一間「不只吃飯，更像品味生活」的地方。 KoDō 和牛燒肉｜極致職人精神，專為儀式感與頂級味覺而生
若要形容 KoDō 和牛燒肉 的用餐體驗，一句話足以總結——「像在欣賞一場關於肉的表演」。 餐點特色
這裡主打 日本A5和牛冷藏肉，以「精切厚燒」的方式呈現。 用餐體驗KoDō 的最大特色是「儀式感」。 綜合評分
地址：403臺中市西區公益路260號電話：0423220312 官網：https://www.facebook.com/kodo2018/ 小結語KoDō 和牛燒肉不是日常餐廳，而是一場體驗。 永心鳳茶｜在茶香裡用餐的優雅時光，臺味早午餐的新詮釋
走進 永心鳳茶公益店，彷彿進入一間有氣質的茶館。 餐點特色
永心鳳茶的餐點結合中式靈魂與西式擺盤，無論是「炸雞腿飯」還是「紅玉紅茶拿鐵」，都能讓人感受到熟悉卻不平凡的味道。 用餐體驗店內服務人員態度溫和，對茶品介紹詳盡。上餐節奏剛好，不急不徐。 綜合評分
地址：40360臺中市西區公益路68號三樓(勤美誠品)電話：0423221118 小結語永心鳳茶讓人重新定義「臺味」。 三希樓｜老饕級江浙功夫菜，穩重又帶人情味的中式饗宴
位於公益路上的 三希樓 是許多臺中老饕的口袋名單。 餐點特色
三希樓的菜色以 江浙與港式料理 為主，兼顧傳統與現代風味。 用餐體驗三希樓的服務給人一種老派但貼心的感覺。 綜合評分
地址：408臺中市南屯區公益路二段95號電話：0423202322 官網：https://www.sanxilou.com.tw/ 小結語三希樓是一間「吃得出功夫」的餐廳。 一笈壽司｜低調奢華的無菜單日料，職人手藝詮釋旬味極致
在熱鬧的公益路上，一笈壽司 低調得幾乎不顯眼。 餐點特色
一笈壽司採 Omakase（無菜單料理） 形式，每一餐都由主廚根據當日食材設計。 用餐體驗整場用餐約90分鐘，節奏緩慢但沉穩。 綜合評分
地址：408臺中市南屯區公益路二段25號電話：0423206368 官網：https://www.facebook.com/YIJI.sushi/ 小結語一笈壽司是一間真正讓人「放慢呼吸」的餐廳。 茶六燒肉堂｜人氣爆棚的和牛燒肉聖地，肉香與幸福感同時滿分
若要票選公益路上「最難訂位」的餐廳，茶六燒肉堂 絕對名列前茅。 餐點特色
茶六主打 和牛燒肉套餐，價格約落在 $700–$1000 間，份量與品質兼具。 用餐體驗茶六的服務效率相當高。店員親切、換網勤快、補水速度快，整場用餐流程流暢無壓力。 綜合評分
地址：403臺中市西區公益路268號電話：0423281167 官網：https://inline.app/booking/-L93VSXuz8o86ahWDRg0:inline-live-karuizawa/-LUYUEIOYwa7GCUpAFWA 小結語茶六燒肉堂用「穩定品質＋輕奢氛圍」抓住了臺中年輕族群的心。 吃完10家公益路餐廳後的心得與結語吃完這十家餐廳後，臺中公益路不只是一條美食街，而是一段生活風景線。 有的餐廳講究細膩與儀式感，像 一頭牛日式燒肉 與 一笈壽司，讓人感受到食材最純粹的美好 有的則以親切與溫度打動人心，像 加分昆布鍋物、永心鳳茶，讓人明白吃飯不只是為了飽足，而是一種被照顧的幸福。 而像茶六燒肉堂、TANG Zhan 湯棧 這類人氣名店，則用穩定的品質與熱絡的氛圍，成為許多臺中人心中「想吃肉就去那裡」的代名詞。 這十家店，構成了公益路最動人的縮影 有華麗的，也有溫柔的；有傳統的，也有創新的。 每一家都在自己的風格裡發光，讓人吃到的不只是料理，而是一種生活的溫度與節奏。 對我而言，這不僅是一場美食旅程，更是一趟關於「臺中味道」的回憶之旅。 FAQ：關於臺中公益路美食常見問題Q1：公益路哪一區的餐廳最集中？ Q2：需要提前訂位嗎？ 最後的話若要用一句話形容這趟美食之旅，我會說： KoDō 和牛燒肉海鮮表現如何？ 如果你也和我一樣喜歡用味蕾探索一座城市，那就把這篇公益路美食攻略收藏起來吧。KoDō 和牛燒肉春酒活動適合在這裡辦嗎？ 無論是約會、慶生、家庭聚餐，或只是想犒賞一下辛苦的自己——這條路上永遠會有一間剛剛好的餐廳在等你。NINI 尼尼臺中店過年期間會開門嗎？ 下一餐，不妨從這10家開始。茶六燒肉堂年節期間價格會變嗎？ 打開手機、約上朋友，讓公益路成為你生活裡最容易抵達的小確幸。茶六燒肉堂小資族值得嗎？ 如果你有私心愛店，也歡迎留言分享，KoDō 和牛燒肉值得推薦嗎？ 你的推薦，可能讓我下一趟美食旅程變得更精彩。茶六燒肉堂再訪意願高嗎？ Researchers at Northwestern University have discovered that the structural features of the brain are near a critical point similar to a phase transition, observed in various species such as humans, mice, and fruit flies. This finding suggests a universal principle may govern brain structure, which could inspire new computational models to emulate brain complexity. The brain exhibits structural criticality near phase transitions, consistent across species, potentially guiding the development of new brain models. When a magnet is heated, it reaches a critical point where it loses magnetization, known as “criticality.” This point of high complexity is reached when a physical object is undergoing a phase transition. Recently, researchers from Northwestern University have discovered that the brain’s structural features reside near a similar critical point — either at or close to a structural phase transition. These results are consistent across brains from humans, mice, and fruit flies, which suggests the finding might be universal. While it remains unclear which phases the brain’s structure is transitioning between, these findings could enable new designs for computational models of the brain’s complexity. Their research was published in Communications Physics. 3D reconstruction of select neurons in a small region of the human cortex dataset. Credit: Harvard University/Google Brain Structure and Computational Models “The human brain is one of the most complex systems known, and many properties of the details governing its structure are not yet understood,” said senior author István Kovács, an assistant professor of physics and astronomy at Northwestern. “Several other researchers have studied brain criticality in terms of neuron dynamics. But we are looking at criticality at the structural level in order to ultimately understand how this underpins the complexity of brain dynamics. That has been a missing piece for how we think about the brain’s complexity. Unlike in a computer where any software can run on the same hardware, in the brain the dynamics and the hardware are strongly related.” 3D reconstruction of select neurons in a small region of the human cortex dataset. Credit: Harvard University/Google “The structure of the brain at the cellular level appears to be near a phase transition,” said first author Helen Ansell, a Tarbutton Fellow at Emory University who was a postdoctoral researcher in Kovács’s lab during the study. “An everyday example of this is when ice melts into water. It’s still water molecules, but they are undergoing a transition from solid to liquid. We certainly are not saying that the brain is near melting. In fact, we don’t have a way of knowing what two phases the brain could be transitioning between. Because if it were on either side of the critical point, it wouldn’t be a brain.” Applying Statistical Physics to Neuroscience Although researchers have long studied brain dynamics using functional magnetic resonance imaging (fMRI) and electroencephalograms (EEG), advances in neuroscience have only recently provided massive datasets for the brain’s cellular structure. These data opened possibilities for Kovács and his team to apply statistical physics techniques to measure the physical structure of neurons. Snapshot of select neurons from the human cortex dataset, viewed using the online neuroglancer platform. Credit: Harvard University/Google Identifying Critical Exponents in Brain Structure Kovács and Ansell analyzed publicly available data from 3D brain reconstructions from humans, fruit flies, and mice. By examining the brain at nanoscale resolution, the researchers found the samples showcased hallmarks of physical properties associated with criticality. One such property is the well-known, fractal-like structure of neurons. This nontrivial fractal-dimension is an example of a set of observables, called “critical exponents,” that emerge when a system is close to a phase transition. Brain cells are arranged in a fractal-like statistical pattern at different scales. When zoomed in, the fractal shapes are “self-similar,” meaning that smaller parts of the sample resemble the whole sample. The sizes of various neuron segments observed also are diverse, which provides another clue. According to Kovács, self-similarity, long-range correlations and broad size distributions are all signatures of a critical state, where features are neither too organized nor too random. These observations lead to a set of critical exponents that characterize these structural features. “These are things we see in all critical systems in physics,” Kovács said. “It seems the brain is in a delicate balance between two phases.” Examples of a single neuron reconstruction from each of the fruit fly, mouse and human datasets. Credit: Northwestern University Universal Criticality Across Species Kovács and Ansell were amazed to find that all brain samples studied — from humans, mice and fruit flies — have consistent critical exponents across organisms, meaning they share the same quantitative features of criticality. The underlying, compatible structures among organisms hint that a universal governing principle might be at play. Their new findings potentially could help explain why brains from different creatures share some of the same fundamental principles. “Initially, these structures look quite different — a whole fly brain is roughly the size of a small human neuron,” Ansell said. “But then we found emerging properties that are surprisingly similar.” “Among the many characteristics that are very different across organisms, we relied on the suggestions of statistical physics to check which measures are potentially universal, such as critical exponents. Indeed, those are consistent across organisms,” Kovács said. “As an even deeper sign of criticality, the obtained critical exponents are not independent — from any three, we can calculate the rest, as dictated by statistical physics. This finding opens the way to formulating simple physical models to capture statistical patterns of the brain structure. Such models are useful inputs for dynamical brain models and can be inspirational for artificial neural network architectures.” Moving forward, the researchers plan to apply their techniques to emerging new datasets, including larger sections of the brain and more organisms. They aim to find if the universality will still apply. Reference: “Unveiling universal aspects of the cellular anatomy of the brain” by Helen S. Ansell, and István A. Kovács, 10 June 2024, Communications Physics. DOI: 10.1038/s42005-024-01665-y Funding: This study was partially supported through the computational resources at the Quest high-performance computing facility at Northwestern. The 93-year-old Xerces blue butterfly specimen used in this study. Credit: Field Museum The Xerces blue butterfly was last seen flapping its iridescent periwinkle wings in San Francisco in the early 1940s. It’s generally accepted to be extinct, the first American insect species destroyed by urban development, but there are lingering questions about whether it was really a species to begin with, or just a sub-population of another common butterfly. In a new study in Biology Letters, researchers analyzed the DNA of a 93-year-old Xerces blue specimen in museum collections, and they found that its DNA is unique enough to merit being considered a species. The study confirms that yes, the Xerces blue really did go extinct, and that insect conservation is something we have to take seriously. “It’s interesting to reaffirm that what people have been thinking for nearly 100 years is true, that this was a species driven to extinction by human activities,” says Felix Grewe, co-director of the Field’s Grainger Bioinformatics Center and the lead author of the Biology Letters paper on the project. “There was a long-standing question as to whether the Xerces blue butterfly was truly a distinct species or just a population of a very widespread species called the silvery blue that’s found across the entire west coast of North America,” says Corrie Moreau, director of the Cornell University Insect Collections, who began work on the study as a researcher at Chicago’s Field Museum. “The widespread silvery blue species has a lot of the same traits. But we have multiple specimens in the Field Museum’s collections, and we have the Pritzker DNA lab and the Grainger Bioinformatics Center that has the capacity to sequence and analyze lots of DNA, so we decided to see if we could finally solve this question.” A collections drawer of extinct Xerces blue butterflies. Credit: Field Museum To see if the Xerces blue really was its own separate species, Moreau and her colleagues turned to pinned butterfly specimens stored in drawers in the Field’s insect collections. Using forceps, she pinched off a tiny piece of the abdomen of a butterfly collected in 1928. “It was nerve-wracking, because you want to protect as much of it as you can,” she recalls. “Taking the first steps and pulling off part of the abdomen was very stressful, but it was also kind of exhilarating to know that we might be able to address a question that has been unanswered for almost 100 years that can’t be answered any other way.” Once the piece of the butterfly’s body had been retrieved, the sample went to the Field Museum’s Pritzker DNA Laboratory, where the tissues were treated with chemicals to isolate the remaining DNA. “DNA is a very stable molecule, it can last a long time after the cells it’s stored in have died,” says Grewe. Even though DNA is a stable molecule, it still degrades over time. However, there’s DNA in every cell, and by comparing multiple threads of DNA code, scientists can piece together what the original version looked like. “It’s like if you made a bunch of identical structures out of Legos, and then dropped them. The individual structures would be broken, but if you looked at all of them together, you could figure out the shape of the original structure,” says Moreau. Study authors Felix Grewe and Corrie Moreau working in the Field Museum’s Pritzker DNA Lab. Credit: Field Museum Grewe, Moreau, and their colleagues compared the genetic sequence of the Xerces blue butterfly with the DNA of the more widespread silvery blue butterfly, and they found that the Xerces blue’s DNA was different, meaning it was a separate species. The study’s findings have broad-reaching implications. “The Xerces blue butterfly is the most iconic insect for conservation because it’s the first insect in North America we know of that humans drove to extinction. There’s an insect conservation society named after it,” says Moreau. “It’s really terrible that we drove something to extinction, but at the same time what we’re saying is, okay, everything we thought does in fact align with the DNA evidence. If we’d found that the Xerces blue wasn’t really an extinct species, it could potentially undermine conservation efforts.” DNA analysis of extinct species sometimes invites questions of bringing the species back, à la Jurassic Park, but Grewe and Moreau note in their paper that those efforts could be better spent protecting species that still exist. “Before we start putting a lot of effort into resurrection, let’s put that effort into protecting what’s there and learn from our past mistakes,” says Grewe. Moreau agrees, noting the urgent need to protect insects. “We’re in the middle of what’s being called the insect apocalypse– massive insect declines are being detected all over the world,” says Moreau. “And while not all insects are as charismatic as the Xerces blue butterfly, they have huge implications for how ecosystems function. Many insects are really at the base of what keeps many of these ecosystems healthy. They aerate the soil, which allows the plants to grow, and which then feeds the herbivores, which then feed the carnivores. Every loss of an insect has a massive ripple effect across ecosystems.” In addition to the study’s implications for conservation, Grewe says that the project showcases the importance of museum collections. “When this butterfly was collected 93 years ago, nobody was thinking about sequencing its DNA. That’s why we have to keep collecting, for researchers 100 years in the future.” Reference: “Museum genomics reveals the Xerces blue butterfly (Glaucopsyche xerces) was a distinct species driven to extinction” by Felix Grewe, Marcus R. Kronforst, Naomi E. Pierce and Corrie S. Moreau, 21 July 2021, Biology Letters. DOI: 10.1098/rsbl.2021.0123 The electrical field-guided migration of Salmonella. Credit: UC Regents Research reveals an electric current in the gut that can attract pathogens such as Salmonella. UC Davis scientists found that Salmonella uses electric signals in the gut to invade the body, a process called galvanotaxis, offering new insights into bacterial infections and potential treatments for diseases like IBD. How do bad bacteria find entry points in the body to cause infection? This question is fundamental for infectious disease experts and people who study bacteria. Harmful pathogens, like Salmonella, find their way through a complex gut system where they are vastly outnumbered by good microbes and immune cells. Still, the pathogens navigate to find vulnerable entry points in the gut that would allow them to invade and infect the body. A team of UC Davis Health researchers has discovered a novel bioelectrical mechanism these pathogens use to find these openings. Their study was published in Nature Microbiology. Bacteria breaking through the gated gut Salmonella causes about 1.35 million illnesses and 420 deaths in the United States every year. To infect someone, this pathogen needs to cross the gut-lining border. “When ingested, Salmonella find their way to the intestines. There, they are vastly outnumbered by over 100 trillion good bacteria (known as commensals). They are facing the odds of one in a million!” said the study’s lead author Yao-Hui Sun. Sun is a research scientist affiliated with the Departments of Internal Medicine, Ophthalmology and Vision Science, and Dermatology. To learn how Salmonellae find their way in the intestine, the researchers observed the movement of S. Typhimurium bacteria (a strain of Salmonella) and compared it to that of a harmless strain of Escherichia coli (E. coli) bacteria. Navigating a complex gut landscape The intestine has a very complex landscape. Its epithelial structure includes villus epithelium and follicle-associated epithelium (FAE). Villus epithelium is made of absorptive cells (enterocytes) with protrusions that help with nutrient absorption. FAE, on the other hand, contains M cells overlying small clusters of lymphatic tissue known as Peyer’s patches. These M cells are tasked with antigen sampling. They act as the immune system’s first line of defense against microbial and dietary antigens. Findings The research that was done on a mouse model showed that Salmonellae detect electric signals in FAE. They move toward this part of the gut where they find openings through which they can enter. This process of cell movement in response to electric fields is called galvanotaxis, or electrotaxis. “Our study found that this ‘entry point’ has electric fields that the Salmonella bacteria take advantage of to pass,” said the study’s senior author Min Zhao. Zhao is a UC Davis professor of ophthalmology and dermatology and a researcher affiliated with the Institute for Regenerative Cures. The study also showed that E. coli and Salmonella respond differently to bioelectric fields. They have opposite responses to the same electric cue. While E. coli clustered next to the villi, Salmonella gathered to FAE. The study detected electric currents that loop by entering the absorptive villi and exiting the FAE. “Notably, the bioelectric field in the gut epithelia is configured in a way that Salmonellae take advantage of to be sorted to the FAE and less so for E. coli,” explained Sun. “The pathogen seems to prefer the FAE as a gateway to invade the host and cause infections.” Previous studies have indicated that bacteria use chemotaxis to move around. With chemotaxis, the bacteria sense chemical gradients and move towards or away from specific compounds. But the new study suggests that the galvanotaxis of Salmonella to the FAE does not occur through chemotaxis pathways. “Our study presents an alternative or a complementary mechanism in modulating Salmonella targeting to the gut epithelium,” Zhao said. Potential link to IBD and other gut disorders The study might have the potential to explain complex chronic diseases, such as inflammatory bowel disease (IBD). “This mechanism represents a new pathogen-human body “arms race” with potential implications for other bacterial infections as well as prevention and treatment possibilities,” Zhao said. “It is believed that the root cause of IBD is an excessive and abnormal immune response against good bacteria. It will be interesting to learn whether patients prone to have IBD also have aberrant bioelectric activities in gut epithelia.” Reference: “Gut epithelial electrical cues drive differential localization of enterobacteria” by Yaohui Sun, Fernando Ferreira, Brian Reid, Kan Zhu, Li Ma, Briana M. Young, Catherine E. Hagan, Renée M. Tsolis, Alex Mogilner and Min Zhao, 20 August 2024, Nature Microbiology. DOI: 10.1038/s41564-024-01778-8 Funding: National Institutes of Health, Defense Advanced Research Projects Agency, Fundação para a Ciência e Tecnologia, Air Force Office of Scientific Research, Office of Naval Research, National Eye Institute. RRG455KLJIEVEWWF |
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